This is very helpful. Thank you.
Yes… Early in the protocol my e2 went through the roof with no AI. I was having terrible sleep, water retention, and prostate complaints.
You are correct - I’m on the 200 mg/ML dosage which puts me at 70mg every 4 days if my math is correct.
As far as SHBG, yes… I’m one of those guys with idiopathic low SHBG. Last time I got it checked (about six months ago) it was 13 (reference range 10-50 nmol/L). I have no blood sugar issues, liver problems, or any of the other culprits typically seen (unless its doing a great job of hiding). I do have sleep apnea, but not sure if that can affect this all that much.
With the low SHBG I get a lot of the free testosterone and E2. The every four days is one day short of twice per week but the numbers come out relatively clean so I have stuck to that routine. If there is something better like EOD I guess I could, but sticking my thigh that often kinda blows.
I’ve been taking the Amdex on opposite sides of the days of the shots for example:
Monday: Shots (70mg test + 250 IU of HCG [forgot to mention that]), Tuesday: Amdex .3mg, Wednesday: Nothing, Thursday: Amdex, Friday: Shots, Saturday: Amdex, Sunday: Nothing, etc…
Also, I know some guys do the AI only once or twice a week… Been there and had terrible results. I have gone to the every 48 hours with the Amdex to smooth it out based on the drugs 1/2 life which seems to be working, but I guess I still need to cut back the dosage. I’m guessing maybe .25 mg EOD, or even more?