T Nation

Does Methodology Affect Results?

I’m referring especially to testing for Estradiol.

For instance, For the Standard Estradiol test, LabCorp uses the “Electrochemiluminescence immunoassay” (ECLIA) method…as does B.C. Biomedical Labs, LifeLabs in B.C. etc.

However…

For the Sensitive Estradiol test, they (LabCorp} use the “Radioimmunoassay” (RIA) method.

Why wouldn’t they use the same method for both tests, unless the RIA method means that the test IS the “sensitive” Estradiol test, which would mean that anyone looking for a lab that performs the “sensitive” Estradiol test in a place where one isn’t specified, could just try and find a lab that tests Estradiol with the Radioimmunoassay (RIA) method.

Unless the methodology used doesn’t make a difference.

Perhaps I’m reading way too much into this, and as long as whatever Estradiol test a man uses has a reference range specifically for males, then maybe that test should be/is good/accurate enough to determine his Estradiol levels…regardless of whether or not it’s an official “sensitive” or “ultra sensitive” Estradiol test.

They key is consistency

[quote]VTBalla34 wrote:
They key is consistency[/quote]

So basically what you’re saying is that it’s best to use the same test (even if the ONLY one available is the “standard” Estradiol test, and NOT the “sensitive” Estradiol test), and the same methodology, and the same reference ranges to determine one’s journey/increase or decrease of levels.

[quote]killergoalie wrote:

[quote]VTBalla34 wrote:
They key is consistency[/quote]

So basically what you’re saying is that it’s best to use the same test (even if the ONLY one available is the “standard” Estradiol test, and NOT the “sensitive” Estradiol test), and the same methodology, and the same reference ranges to determine one’s journey/increase or decrease of levels. [/quote]

Basically. What other option would you have if you can’t access the right test?