I have believed this in the past. Now I don’t.
I am now 56 and have been on TRT only for nearly 6 years. TRT has enabled me to continue to be very active… skiing, mtn biking, hiking, lifting and swimming. Substantial efforts as well.
I inject weekly and would often feel very rundown on injection days and the day after… especially if my activity level was high. Felt like I was just out of T. I was injecting 180mg weekly and keeping my blood levels above 1000. After high activity, I felt worse, but the tests did not reflect how I felt. I did try more frequent dosing, but that did not improve my situation.
I also tried lower doses and that didn’t help either. I endured this situation for 4.5 years.
What really changed happened by accident. I am also low thyroid and take Synthroid. Was never really diagnosed other than high TSH. My reading here convinced me to poke around my thyroid issues and I decided to start taking iodine and selenium supplements. I took 31mg of potassium iodine every day for 2 months to load up the thyroid and then cut back to once a week. I also stopped my Synthroid to see how my thyroid responded.
Well, that experiment failed miserably. My TSH skyrocketed and I had to start taking the Synthroid again. But, I noticed my injection day fatigue was gone. I cut my T dose to 100mg weekly and still did not have the fatigue. I did have low estradiol, so I upped my T to 140mg weekly. Been at this level since January and feel I have finally found the TRT sweet spot.