Does E2 Raise SHBG or Does SHBG Lower E2?

Definitely don’t try clomid for lowering SHBG. It will have the opposite effect.

I’ve tried Clonid alone before TRT, it did nothing.

Prior to TRT, and prior to Cyp EOD my SHBG was normal. Looks like it’s either frequent small doses of Cyp, or workouts or beer… Nothing else comes to mind. Please clue me in other possibile causes.

http://blog.insidetracker.com/sex-hormone-binding-globulin-new-science-questions-old-beliefs

Is it free DHT that affects prostate in terms of PSA (and causes acne), not total DHT, right?

So if someone’s total DHT is high but free DHT is low for whatever reason then DHT does not affect prostate/acne?

What about free T vs total T ? Same concept?