T Nation

Do SSRI/SNRIs Increase Cortisol?

I’ve googled fairly extensively but can’t find any scientific studies or conclusive evidence.
I found one article claiming that one dose of Prozac or similar SSRI doubles cortisol levels and leads to adrenal fatigue, but didn’t back it up with any references.

Just wondering, as that could seemingly explain a lot of side-effects myself and others experience with antidepressants.

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Aren’t there some drugs that increase the effects of both serotonin and dopamine? Maybe you could get one of those prescribed…

What exactly are the experienced symptoms?