Thanks methos. I'll have Doc check free t next time. I've read that optimal E2 is in the mid 20's. I also has E2 checked back in june, a month int the 150 mg dose, which came back at 63. So it looks like E2 is coming down a bit. I felt great during the second and third week (libido / energy / mood) but for the last month, libido has decrease. Which is the reason why E2 levels were a concern.