Depression, High Ferritin, High E2, High SHBG, Low Free T

Should have E2 results from Nov in a day or two. My SHBG is basically unchanged from my initial test and it’s at the high end of the average range.

SHBG
Jan 2016- 61 nmol/L [17-66]
July 2016- 62 nmol/L

How are you finding the arimidex monotherapy? Did you do this through a doc? If my E2 and free test levels don’t improve over the next 6-8 months I feel I may have to look into this. Who knows, things may improve with further venesections. Excess iron in the body can and will find it’s way into the testes and do damage.

I guess the problem is finding a doc in Australia that is willing to do it. I could source it via a questionably legal method, but it’s pretty expensive stuff and i’m a bit worried if the supply suddenly disappears. Once you start using Arimidex is it for life?

Never had an ultrasound on the balls, no pain or anything there.

The monotherapy has been both good and bad. While it initially brought my levels down to a respectable point, and I felt bloody amazing (libido, boners, energy) the whole shabang! But that tapered off as E2 kept getting lower and lower until it crashed. Now I am toying with a super small dose (0.125mg EOD) and seeing if I can stabilise these bloody E2 levels.

I’m in Aus also. It is EXTREMELY hard finding a doctor who will prescribe you Arimidex. Mine did. Before I got it prescribed, I sourced it illegally in Aus. One box will take you a long way. And is it for life? It depends. If your situation changes, then maybe not. But if your body doesn’t really change and it keeps operating the way it does now only Arimidex is lowering your E2, when you come off it will just go back to where it used to. If you can find the source of high E2, and fix that while you are on the Adex, that is the best thing to do.

My doctor says it is my viscerial fat which is aromatising too much (the fat in between my organs) and the Adex to control should allow me to burn that, maybe in 6 months time to perhaps a year. Then hopefully when I go off the Arimidex, the situation could change. It is not a guarantee though. That’s just an example.

Haha good job finding that doc. Yeah, I already did the math that one pack would last quite some time. Very interesting, thanks for your comment.

Just thought i’d post an update as it appears I have made significant progress in my mental state and fatigue/anxiety is nowhere near where it was at previously.

So for quite a while a suspected the problems to stem from either my HSV-1 viral infection, high E2 or high transferrin saturation. I can’t remember exactly how many phlebotomies i’ve had, but as of late December my ferritin was 25 ug/L (nice and low). I’m very curious as to my transferrin saturation, but they didn’t test for that in Dec. I carefully drove my E2 via pharmaceutical means and noticed no difference at all. So i’m guessing the high iron may have caused a deficiency in zinc (and possibly not enough in diet) because I bought a bottle of the taste test liquid zinc and found there to be very little taste. After smashing the zinc for a few weeks (90-120mg per day) and continuing on 30mg a day for 2 months, the liquid zinc has a much stronger taste.

Now, in Jan I had androgen & endo studies done and my TT had gone up to 18 nmol/L (519 ng/dl) from 16.4 nmol/L (473 ng/dl) and my E2 down to 91 pmol/L from 137 pmol/L. This was a really great result for the E2. I was pretty pleased with such a big reduction. I was still feeling like absolute shit though.

Fast forward to now, and I decided to stop watching porn and masturbating, which I was doing once a day or every two days. I’d tried nofap before after reading about it on reddit but could never commit to it for more than a few days. About 8 days in the difference was absolutely night and day. Even with suboptimal sleep, my mood was more positive, I had less anxiety, more confidence, improved concentration and better emotional stability. When I got home and jumped in my squat rack, I observed there was a noticeable increase in strength. Anyway, this is what worked for me. I’m only 12 days in and am blown away by the difference in quality of life this adjustment has made. Obviously this can be a very hard thing to commit to and i’m sure there will be a slip up at some point.