I dont think anyone really knows if it’s better to take DAA on an empty stomach or with food. Here’s what the researchers did:
“Every morning at breakfast for 12 consecutive days subjects in the first group were invited to consume, by mouth a solution of 10 ml of 2.0 M sodium D-aspartate (3.12 g/10 ml) supplemented with vitamin B6, folic acid and vitamin B12 and diluted in half a glass of water or fruit juice. This solution is marketed in Italy under the name DADAVITÂ® (Pharmaguida s.r.l., Italy) and used as a supplement to increase the quality of human seminal fluid.”
Since blood was sampled in the morning (24 hr after the previous dose), it is unclear if DAA has an acute effect (not likely IMO) or a chronic one. It would also be interesting to know what happened to free T, the ratio of T to E, etc. Hopefully, some of the companies that are making $ off DAA will step up to the plate and sponsor some research.
Bottom line: Until we know more, take DAA like the subjects in the study did (on an empty stomach).
Thanks for the update. The stuff looks promising and I can’t wait to see what Biotest does with it!
If you have looked into it, can you comment on whether there is potential for competition for absorption of this amino acid if taken with other aminos/protein, meaning can this stuff be taken with food??. FWIW, E-pharm recently released their DAA product, and the directions say to take it on an empty stomach.
Also, I imagine that dosing this right before a workout would be beneficial, although given the empty stomach recommendations, I would think it would be pretty hard to do this, especially if on the anaconda protocol, since “take it on an empty stomach” usually means 30 min before other food.
maybe taking this in the morning with a carbohydrate and BCAA shake would be okay? Or do the branch chain amino transporters compete with those of D-asparate?
Also any other comments on the cognitive aspects if you or anyone else have any? Thanks![/quote]