Someone peaked my interest to these compounds on another website. They are a saturated fatty-acid’s w/ a added sulphur molecule. The one I am specifically interested in is called “3-thia”. I did a pubmed search and was astounded to find more then a few studies on their possible health benefits. Here is an abstract from a review article that summarizes some of the possible health benefits:
“Thia substituted fatty acids are saturated fatty acids which are modified by insertion of a sulfur atom at specific positions in the carbon backbone. During the last few years pleiotropic effects of the 3-thia fatty acid tetradecylthioacetic acid have been revealed. The biological responses to tetradecylthioacetic acid include mitochondrial proliferation, increased catabolism of fatty acids, antiadiposity, improvement in insulin sensitivity, antioxidant properties, reduced proliferation and induction of apoptosis in rapidly proliferating cells, cell differentiation and antiinflammatory action. These biological responses indicate that tetradecylthioacetic acid changes the plasma profile from atherogenic to cardioprotective. As a pan-peroxisome proliferator-activated receptor ligand, tetradecylthioacetic acid regulates the adipose tissue mass and the expression of lipid metabolizing enzymes, particularly those involved in catabolic pathways. In contrast, circumstantial evidences suggest that peroxisome proliferator-activated receptor-independent metabolic pathways may be of importance for the antioxidant, antiproliferative and antiinflammatory action of tetradecylthioacetic acid.”
- cardio protective
- increased mitochondria proliferation
- Positive impact on metabolism and body composition
- Anti-O activity
- cancer fighting
All this at a dosage similiar to 1 gram a day.
Many of the studies were in vivo or in rats but I still had difficulties finding ANY negative effects in the literature. Some of the researchers seemed to suggest they worked via PPAR antagonists which I have read isnt always a good thing.
Anyways, I was hoping you two could shed some light on these compounds for me. I know Lowery loves his fats
For anyone interested search pubmed or google for “3-Thia”.