So it’s been a couple weeks and I finally have some time, and better yet, some experiences to share as an update.
I’ll start with my needle experiments.
Experiment 1: backfill vs draw on 27 and 29 ga
I have had no issues drawing on either 29 or 27 ga. The needle does pierce the skin noticeablely easier with back filling instead of drawing. The rubber stopper does dull the needle a bit. It is more noticeable on my 29 ga needles than the 27 ga. The hassle of back filling isn’t worth it to me however so I have been drawing regularly now, still, it was a fun experiment.
Experiment 2: using same syringe for Test as well as gonadorelin.
Once I gave up back filling due to the hassle, I had to give up using the same syringe for both. As mentioned above, poking the stopper does dull the needle, as does poking the skin, so two rubber pokes and two skin pokes on the same needle gets very dull and increases bruising (one bruise was golf ball size) Wasn’t really worth it. A heavier ga might hold up better, but these 29 and 27 ga insulin needles are too spindly to hold up to 4 pokes.
Experiment 3: needle brand
BD vs Easy Touch needles. I think the BD needles are a bit better. I would and will gladly use both brands, but all else being equal I would pick BD as any air bubbles are easier to get out with the BD syringe design, and are a tiny bit more consistent in sharpness.
As far as bruising goes, I am getting better at this now. I no longer pinch, touch, or hold any skin, I just jab it in. Also, I no longer hold the syringe near the needle end, only at the plunger end. I inject slow and steady and this technique “floats” the needle end rather than have it tug on the skin as my hand moves around a bit.
Now on to the gonadorelin. This has a terribly short half-life. Only 4 min in the blood stream as I found out. I found a few studies (not based on trt in any way) that tracked the effects. Once the receptors are stimulated by the gonadorelin the raised LH levels last for about 4 hours or so. I find my results mimic the study exactly. Takes about an hour or two to slowly kick in then last for about 4 hours and fades. My daily dose is not enough to notice, but if I do say .25mg at once it is mildly noticeable. The drug as designed is a 1mg single dose to test pituitary gland function. My prescription is for .5mg per week. I can see why guys are trying every 4 hour dosing, but those intervals are not practical, and my prescription would make the dosing amount ineffectual in my opinion.
The drug as designed should raise LH 4x on average over the 4 hour period, peaking after about an hour or so, then tapering off. This done at the 1 mg dose. My .07 mg dose every day is not really noticeable for me. The .25 mg dose is lightly noticeable, but that can only be done 2x per week limited by my prescription. I tried both dosing regimes. Not sure which i want to stick with for the next 8 weeks. I will definitely be asking for HCG with its 2.5 day half-life next time, but as I have 8 weeks to go on my current prescription I want to make the most of it. The good news is that with a 4 minute half life and roughly only a 4 or 5 hour effect on LH, fiddling with dosing can be noticed from one day to the next without much carryover. I’d try the full 1mg as prescribed for pituitary testing, but I don’t want to use 2 weeks worth of it on a single dose. My primary purpose for it was fertility in the first place, so I’m hesitant to use it less than 2x per week. That said, the .25mg does that was mildly noticeable was an overall positive experience, so I think there is potential here, just not sure how to make the most of it. I suspect the industry in general is still working this out.
The general effect of the .25 mg gonadorelin dose from a very anecdotal perspective was that of a very mild increase in libido and energy, and all around feeling healthier, if that makes sense.
Now on to the Test C. I have had a bit of a mixed bag on this. In general it has been life changing, but in general my experience has been a bit odd. Maybe you guys can help me on this. The first day was not much of anything. Day two I had an increase in energy. I slept way deeper, but slept less as I have been crazy busy at work. Day 3, even after only 4 hours of sleep, I felt 100% amazing. Better than I ever have before. I felt better than I knew was possible. Insane. By day 4 even more so, though I only had 4 hours of sleep that night as well. Now I’m on my 4th day with only maybe 17 hours of sleep over the 4 nights and I still feel great. I knew this could not be sustainable as eventually I would need more sleep. After the first 5 or so days I have slowly but surely came back down to earth. I do feel better now than before I started trt, way better, and I have gotten normal sleep the last few days, but i feel nothing like I did from day 2 to day 6. Any guesses on why I had such a crazy response those first few days?
This last week has been more what I expected. I have way more energy. I sleep much deeper. I feel more rested when I wake up. When I fall asleep it’s because I’m sleepy, not like before when I would go to bed not sleepy at all but a total wreck. My joints feel better any my headaches and sinus pressure is also way down. All great stuff.
I am in general larger too. I have been more thirsty, especially at first, and put on over 5 lbs. My muscles are “fuller” and even though I have been too busy to work out the last couple weeks, I have visually made more “gains” in two weeks than the last 4 months. This has leveled off, but I did add what I assume to be water to my muscles, probably due to an increase in estrogen? It has been enough people have commented on it.
The only disappointment so far has been with libido. I did read that it can take 3 to 6 weeks to increase, but as so many of my other effects came on so strong and rapidly I was hoping for more improvement here. It is better for sure, but to go from 1% to 5% is not exactly what I was hoping for. Sure a .25mg dose of gonadorelin gets me up to 20% for a few hours that day, but in general this has been underwhelming, and the .07mg dose does not seem to do anything for libido. And actually, as with all things Test C related for me so far, I actually noticed a way bigger increase in libido the first few days than I do now. Again not sure what’s up with that.
As a side note, all of this has been done on daily morning SubQ injections. As gonadorelin has such a short half life, I am switching to night time injections. I’ll let you know how that works out for me. Also, having done the .25 mg 2x per week gonadorelin and the .07mg daily, I’ll probably stick with the daily routine unless something sparks my interest to try something different. Very curious to see how HCG differs from the Gonadorelin with my next prescription fill.
I am getting very curious where my blood levels are and will be super excited for when I get to retake my bloods in a few more weeks. I’ll be sure to share those as soon as I get them. It took just shy of 2 weeks to get my prescription to me last time, so I’ll need to take them around week 6 if I expect to get my results in time to have them be of use before I need call again for my next batch, so first week in June or so. Work (the new job had a lot of catching up to do) is a bit more normal now, so I will have more time to keep up with this thread if there are any questions or comments.