I'm 29 years old and have had fatigue and brain fog for a while. My last free T was 11.5(reference: 9.5--26.5) and my total T was 563(reference: 280-800). E2=60(reference=7.6--42.6). I was taking ORAL compounded DHEA 100mg at the time as well as 100mg of sublingual Pregnenolone drops. Now using sublingual compounded DHEA drops approx. 50 mg/day. Stayed on same dose of pregnenolone. Also take One grain of Armour BID. Other results of note:
TSH=0.428 Low(secondary to Armour)(0.450--4.500)
Cortisol=12.4(2.3-19.4)Taken at Noon.
Cortisol is affected though b/c I take Adderall which will artificially raise it. So I'm wondering if it would be REALLY low without the medication. I know 24 hour salivary is better(I'm in the medical profession with a Doctorate degree), but I can't stop the medication just randomly like that. Still cold a lot with low energy. I'm wondering if high E2 is blocking T4-T3 conversion? Why is rT3 high? Someone said it should be 1/3rd of T3, but that doesn't make sense with the reference numbers I have from Labcorp.
Other important facts:
Vitamin D level is fine=60
Have high Candida levels(have eradicated in the past but comes back)
Low Alpha Melanocyte stimulating hormone which is likely behind ALL of this. Read the book Mold Warriors to learn a ton about hormones and how the immune system is involved with them intimately not just by draining the adrenals but b/c Alpha MSH is a MASTER HORMONE.
I felt much better while on high dose Resveratrol, calcium d glucarate, and myomins--sex drive went way up, strength went up, erections were better and semen volume was way up!
Will have Thyroid binding globulin and SHBG measured soon.
Body fat is around 18% despite lifting 3-4 days a week and taking fish oil, digestive enzymes and Betaine HCl.
It's good to get others' opinion as knowing as much as I do I go around in circles!