I ran some more test. Also, found a hormone replacement doctor who offers concierge service. I ran my labs again (CBC, Lipids, Test, Thyroid), and cholesterol is low due to dieting and heathy eating. He wasn’t too concerned. Actually, he said my labs were good, and I shouldn’t be too concerned.
I did my thyroid tests again, checked for auto-immune stuff, all came back negative and normal. The high estradiol levels were from the Clomid. My test levels dropped from 1266.3ng to 604ng after being off the Clomid for 6 weeks. I believe my baseline is around 400s… My estradiol levels dropped to 18 pg/mL, too, so it was from the Clomid. I did notice some strength and energy loss coming off the Clomid.
I started a new protocol last week - taking anti-estrogen supps, and Clomid 25mg for 2 days on, and 1 day off, and have noticed mood has improved, as well as strength and energy. I feel great. See details below…
Apparently, a doctor out of Florida has done some research on Clomid, and some men have the issue where E levels rise too much with the use of Clomid. My local doctor wanted to try either 25mg Clomid EOD or 25mg Clomid every 2 days with 1 day off. I’m also running I3C, Calcium D-Glucarate, and DS Triazole every day to see if it helps estradiol levels. I’m going to cycle off of the I3C, Calcium D-Glucarate, and DS Triazole every 8 weeks, with a 4 week break. Doc told me to let him know if I need Arimidex, but just don’t want Arimidex, want see if there is a holistic approach to this, first. I don’t know if it’s good to cycle on/off Clomid, too since that causes a change in hormones. There is still so many unknowns with long-term use. The only research I’ve found is one conducted in the UK with a group of men for 3 years, and there weren’t any issues. Also, further research shows even HCG doesn’t hold up long-term for some, and Clomid is still a better option for those wanting to preserve fertility.
I changed my workout routine as well, AST might be from my previous routine, yes, sore muscles. I’m going to run full labs again in 8 weeks, and will post results. I don’t want TRT therapy since we’re wanting more kids. Also, it seems many of the TRT options have just as many unknown side effects, if not worse. Positive note, my wife is pregnant, and we’re having a healthy baby girl, so Clomid definitely helped.