We do caution against high clomid doses for good reasons and your high E2 is predicted. We try to get guys on TRT near E2=22pg/ml.
While the SERM does protect selected tissues from the effects of elevated tissues, your fat cells, brain and liver are probably not. Liver sees high SHBG and it responds by increasing SHBG that lowers FT fraction. You can become bitchy and have adverse fat gain and patterns. Oddly, a few get gyno.
SERM is causing high LH=8.9 and creating high E2 from high T–>E2 inside the testes and anastrozole cannot work there. So you can’t fix this that way.
Doctors do not get it, deductive reasoning was not part of med school.
Also high E2 blocks some T action at T receptors, reducing effectiveness of what Bio-T you have. And high LH/FSH is though to fatigue receptors in the testes, a step backwards.
In the future, always include lab ranges.
Please read the stickies found here: About the T Replacement Category - #2 by KSman
- advice for new guys - need more info about you
- things that damage your hormones
- protocol for injections
- finding a TRT doc
How old are you? Needing TRT or need to fix HPTA?
TSH=1.51 is starting to get interesting. The lab range is useless and you would be better off near TSH=1.0
There may be a problem if you have not been using iodized salt.
Do not think that this is a tangent to your state of health.