" But this is not all that scientists have learned. During the experiments aimed at stimulating the synthesis of gonadoliberin, it was found that the drugs mentioned above have completely different effects. So can athletes not be mistaken, believing that Nolvadex is a more powerful drug, and in general that it should be taken for other purposes than Clomiphene ? Let’s find out.
In the tests, 100 g of gonadoliberin was administered to volunteers and the amount of LH synthesized was measured. Thus, scientists tried to find out how much the sensitivity of the pituitary gland to this substance, if you enter Nolvadex or a clomiphene similar to it. This was done for one simple reason: as is known, the more sensitive the pituitary gland, the more LH synthesized, and, consequently, the higher the level of secreted testosterone.
This means that the more effective the drug contributes to the action of gonadoliberin, the more it affects the restoration of the level of the male hormone.
The results of the test are as follows: the use of Nolvadex within 10 days increased the sensitivity of the pituitary gland to gonadoliberin several times in comparison with the usual parameters. Clomiphene, in turn, had the opposite effect. That is, the sensitivity of the pituitary gland at the time of its reception has decreased on the contrary.
The dosage of Nolvadex and the rival drug was taken to be comparable in capacity (20 and 50 mg). The result of all of the above is simple: Tamoxifen copes better with increasing the sensitivity of the pituitary gland, and therefore, more affects the secretion of LH and testosterone in the male body, rather than its competitor."