Anastrozole is a competitive drug that interferes with T at aromatase enzyme reaction sites. The goal is E2 modulation, not elimination. AI drugs reduce FT-->E2 generation, but do nothing to reduce existing E2 in you body. Your liver clears E2 from your body. Some drugs, some gear or liver conditions can reduce E2 clearance in the liver, so E2 levels rise.
E2 labs: Please be on a steady dose of anastrozole dose for 7-10 days prior to labs. Try to feel your way into a dose that seems somewhat beneficial. Then lab results can be used to calculate a dose refinement. Like sighting a gun, you can't get dialed in if you are not hitting the paper [target].
If you get E2=32pgml.
Target is E2=22pg/ml
New anastrozole dose is old anastrozole dose X 32/22
yes, that simple
It take a week for a dose change to work, making fast snap dose changes is a disaster. It is all about the half-life that I will not explain further.