Can Testosterone Cause Depression?

Will take your advice on lowering it gradually. Will estrogen take care of itself without me needing to do anything for it during this decrease?

Please show me your evidence that demonstrates “sky high” estrogen causes ED. I can send you at least 20 examples of men with E2 over 100 who have ridiculous libido and raging erections. Considering estrogen is directly responsible for libido and erections, this is unsurprising. Of course, these men have optimized free T levels.

If a man has “sky high” E2 with ED, he probably has low levels of testosterone. This is typical of obese men with cardiovascular disease.

I don’t know why this misinformation continues to be spread here with everything we know now on this subject.

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No photos please. LOL.

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Your body will regulate your estrogen. Go into the dose drop with the expectation that you may not feel great for a little while and there’s no quick fix. Give it time and you’ll get to a place where you feel good.

All said in this statement sounds logical to me.

However I can not agree that 700ng/dl for example or 650ng/dl should be enough total testosterone to relive symptoms. Most men here maintain much more. How likely it is that a number on a piece of paper will determine whether you should have enough or not? Isn’t this similar to the absurd stupidity of the “you are in range” said by almost every endocrinologist out there?

Also what about androgen receptors sensitivity that is different on everyone? If there is one think Im 100 percent sure in regards to TRT is that everyone needs different amount of testosterone to feel optimal, both total and free

Again you’re seeing things one way, your way. I see a lot of men having erections issues with estrogen above range.

If you pay attention to what goes on in these forums you don’t need evidence, you only need to pay attention the symptoms.

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I feel like Im gonna be the Cialis guy on this forum. Lol. Bro, pop 2.5mg of Cialis generic at night, before bed. Let your body do its thing. Cialis helps get a better T/E ratio, plus you will start having nocturnal erections that could wake you up by surprise. Then morning wood will start to make its appearance. Do this to bridge yourself into a better place. The lack of erections will do a number on your mind. I know that youre 19, but this should help you bridge your dick back to a healthy state. Lower your T dose and meditate a bit, in order to relieve the anxiety.

I’m not seeing things my way. I can demonstrate this 100 times. Again, the main thing that affects your judgement here is your 7mg a day of testosterone protocol. This DOES NOT work for 99.9999% of the population. You need to have sufficient levels of free T (more than you’ll ever agree to) and you never have to worry about estrogen when that is done. I know you’ll never understand this but I’ve seen this countless times with the guys I’ve worked with. It’s demonstrated over and over and over. Estrogen is directly responsible for libido and erections and you need good levels of free T at the same time. Your opinion of optimal free T is nowhere near what optimal is for everyone else.

Again, this isn’t just my opinion (even though I see deal with this literally every day). This is 15+ doctors sharing with me what is working for their patients and what isn’t. We’re talking about thousands of men here.

My advice is based on what works. Not hearsay. Not the experience of a handful of guys. It’s the results from thousands of people delivered straight to me by some of the top physicians in the world.

Here’s the other thing. If you have total T of 700 and your symptoms have improved since starting trt but are not quite resolved yet, what now? Do you stop because of a number or do you bump up the dose to see what effect it has?

In a perfect world we would be on a deserted island, have testosterone available to us, no docs, no labs. What would we do? We would figure out how much we need to take a week to feel better. It would be so damn simple.

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I dont feel good now either so yeh, constant headache, tired eyes. Maybe because I took a week off gym because I was kinda “sick”.
Ill just drop down to 200mg / week from this week onwards and see how long it takes.

This could be related to something else but I constantly feel like I m in space, tired eyes even after 8 hours of sleep, constant mild headache, etc…

Once again bro, nobody asked you. I highly suggest you pay a visit to a phychiatrist to address your OCD related to spamming dozens of threads a day with your 7mg dose.

Funny you mention that. That is EXACTLY how I found what works for me to feel fantastic.

Of course, I will be doing bloods down the line to assess health markers. But thats a totally different topic altogether.

Again you took didn’t see my point, I was trying to show how far off the mark this is in dosing, another example of how microdosing can work for people not feeling well on large infrequent dosing.

You’re not very amusing at all, this isn’t high school, try to act like an adult.

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Get out of here with that shit.

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Splitting up a large weekly dose into ED or EOD is completely different to what you are doing! By all means, suggest breaking up a dose. And in this case by all means suggest to the OP that he reduces the dose from 500mg to 200mg or even 150mg.

But to 49mg/week? The OP said he’s original blood levels were 350 both pre and post TRT. That is around the same figure you are aiming for yourself with 49mg\week yes? So whats the point in your suggestion ?!?!?!?!?!

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@tfan866

If @systemlord felt fine at that dose, so what? He has low SHBG and if you believe that freeT determines how you feel (and there is a decent amount of evidence for this) than he may not need more than 450 ng/dl to have an ok freeT level.

I do 70mg per week split into 3 injections. Works perfectly well for me. Brings my freeT to around 12 ng/dl (from 6 preTRT) which is the average for my age and I feel super fine.

Its like coffee. My brother needs 5 per day otherwise he falls asleep at work. If I have more than 2 I cant sleep and stay up all night. We are all different.

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It’s no problem whatsoever that he feels fine at that dose, as I suggested to him in another thread he should keep a detailed log of his own. The fact that he feels the compulsive need to mention his dose in each and every other thread every single day is whats the issue. It will end up having a resultant effect like E2=22.

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Nice analogy.

Here’s my take on this: let’s say I would start telling people not to drink coffee because if they do they won’t be able to sleep for 2 days. Let’s say I said that because it was my experience (it isn’t in reality… Just making an example). If I gave out that advice it would be viewed as silly by most people because ‘most’ people can drink coffee without issue.

When I give advice, I’m basing it on the majority. I’m basing it on the fact that 80%, if not more, do better with a higher dose. Yes, he may fall outside that 80% but, statistically, I have more chances of getting it right than telling him he’s going to be one of those 5% outliers. If he is, we will figure that out quickly. I’ll put my money on the 80%.

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I can’t even tough coffee unless it’s decaf, I’ll over-respond to the caffeine and will start shaking uncontrollably. It’s no surprise I over-respond to some medications.

Ksman was many times smarter than most of us on this forum in key areas as far as I’m concerned, but never did agree with the anastrozole 1mg per 100mg cypionate or the E2=22 sweet spot. Some guys feel like death at that E2 number.

I believe a lot of guys have actually quit TRT do to targeting high testosterone when they actually would have found success getting FT about midrange and slightly higher, but a lot of guys are frightened about lowering their dosage too much for fear of a return of low T symptoms thinking more is always better.

Guys with anxiety/depression disorders I notice do better in microdosing since the moderate to larger injections tend to cause spikes on testosterone and estrogen which can exacerbate anxiety.