I'm in PCT right now taking 40mg Nolva/day and 1mg Letro/day both of which I will be tapering over the coming weeks. My existing gyno had been fine (excellent) taking Letro on cycle (I was also taking Masteron which I suspect helped as well). When I finished my cycle I changed 3 variables around the same time so I'm not sure which exactly caused it but my gyno is a little more swollen than I would like 1 week into PCT. Here are the 3 variables I changed: stopped injections of test prop and mast, introduced Nolva 40mg/day and about 1 week before the end of my cycle I dropped my Letro dose to 1mg/day (because I was really dying from low estrogen side effects).
To get to the point - 1 (or more) of those changes have caused the breast tissue to swell (or grow). It could be because I reduced the Letro to 1mg/day and I'm experiencing estrogen rebound(which seems unlikely to me because 1mg/day is still a huge dose I think) OR I was thinking that it could be related to the subject of this thread. What I mean is - since being an estrogen antagonist Tamoxifen Citrate is a molecule that has a similar structure to estrogen, is it possible that the Tamoxifen Citrate molecule itself could have some (transient) effects on the breast tissue? In other words, could Tamoxifen Citrate actually cause some swelling as it binds to the estrogen receptors in the breast tissue to prevent the actual estrogen from binding? I think that I had read this concept before somewhere but I'm not sure...