It depends how far past your natural genetic limit you are.
Any amount past what you produce naturally is going to enhance you. As you progress further and further you will essentially need more and more to keep progressing. This is not however anything near the level of increase that most seem to employ (adding just 100mg per cycle is FAR above what is necessary).
But of course, you WILL grow more if you include other drugs (all else being equal - if the other factors such as training, diet, rest are not, then one shouldn’t be using PES) - insulin and GH namely, as the two other hormones involved to a large extent in the growth of muscle (plus the hormones that are associated with them such as IGF, etc.).
As for 500mg being all you need… it depends on the person, it is not the case, nor has it ever been that one can say “x amount of AAS is all you need for y effects” as they are drugs and dosing will vary by person.
This is one of the issues i have with the stickies, although i understand their need.
I honestly have been saying this for some time. Having run something like (approximately) 20 cycles now i still only use around 1g/wk as standard (sometimes more, sometimes less).
(of course this wasn’t the case by default and it took using larger doses over 1-2 cycles to learn this - or at least to form this opinion…)
Lastly on the topic of 500mg - you have to offset the level of inhibition you will have with the level of (therapeutic) effect which may suggest you would opt for a little more… but i agree fundamentally.[/quote]
agreed on all points…one piece of what i consider “great news” i think you all will too. After using whatever you choose to for many years (ie me) and develop a large amount of size (around 300lbs for me) then going on hrt for a few years and trimming back (250ish) i found much to my very pleasant surprise that i can very quickly put weight on with just a small boost in drug dosage. I went from a whopping 100mg of test to an enormous 200mg dose per week and added one thing, 200mg eq per week. within 4 weeks i was back at 270 which was somewhat shocking in a good way. Why the eq? well i didn’t want to get back on high doses of anything since i have to have blood work every 16 weeks, and there is one thing eq does better than any other drug IMO…makes me eat like a horse. So i contribute my gains primarily to the fact that i am back to a ravenous appetite, along with a small boost from the increased testosterone dosage. So…what i am getting at in an admittedly rambling manner is that your dosages will escalate over time, but with proper re-adjustment and off time (or pseudo off time in my case) you will once again respond to small doses, even if you are above your pre-determined genetic ceiling. The main factor i believe is CHANGE, a rapid influx of nutrients, combined with hormonal support.