I’ve spent many months researching and becoming comfortable with the idea of TRT before deciding to take the plunge. I tried once before, with a terrible protocol for my needs (200mg/wk) and my dick broke, anxiety went through the roof, and I ran away scared, but determined to become more knowledgeable and prepared.
Having said that, I’ve been on TRT now for 11 weeks @ 50mg E3.5D. The first 4-5 weeks, everything “clicked”. Sex drive through the roof, anxiety completely resolved, confident, motivation to go to the gym was incredible… I felt like a completely new man. At 6 weeks, I had bloods taken. The doctor was pleased with the results, and because I felt great, we kept as is. Immediately after, I started regressing… Frequently tired, morning erections more intermittent, sex drive dropped, anxiety started rising again. I’ve stuck with my protocol and intend on going for more blood work soon - However I’m curious if there’s anything in my current bloods that might help indicate why I’m struggling.
35 years old
Overweight - 6’/275lb - Thick build. I powerlift, wide shouldered. I’m thin at 225lb/happy at 240-250. I lost roughly 100lbs (peaked 375lb) over the past 4 years to try and handle this situation naturally, but my test levels were actually even worse down 100lb. So here’s a breakdown of my results thus far:
Pre-TRT Bloods (run at my Dr’s office - I believe Quest Labs**):
Serum Testosterone 338 ng/dL (348-1197 range)
Free Testosterone 6.51 ng/dL (4.7-24.4 range)
Estradiol 21.1 pg/mL (25.8-60.7 range)
6-Week Test Results @ trough (3.5 days after last shot, right before I pinned)
Tested by LabCorp***
Serum Testosterone 811 ng/dL (264-916 range)
Free Testosterone 18.7 pg/mL (8.7-25.1 range)
Estradiol 26.5 pg/mL (7.6-42.6 range)
SHBG 28.8 nmol/L (16.5-55.9 range)
Sooo…. Estogen spikes (tough to know without testing peak right?)? Not enough free T? Any thoughts or suggestions? I’ve considered daily SubQ pinning, but my work schedule involves a lot of travel, and I’d like to stick with this current E3.5D protocol if at all possible… But if everyone agrees that this could be estrogen spike-related, I can be openminded if absolutely necessary… Sorry for the lengthy post and thanks in advance.