After reading the study you posted I’m amazed at the innumerable benefits this mineral provides. I saw you stated that every single patient begins boron after 6 weeks on trt.
“It is well known that approximately 98% of testosterone molecules are bound to proteins in the blood, principally to sex hormone–binding globulin (SHBG), and are not bioavailable because bound hormones cannot exit capillaries.22 Thus, the elevation of unbound free testosterone seen with boron supplementation may have significant beneficial ramifications, particularly in aging men in whom, typically, levels of SHBG increase and levels of FT decrease.”
Does this imply that boron is reducing SHBG?
Edit: I see Unreal may have addressed this already above. @unreal24278 is there any risk of tanking E2 with boron?