Glossary
DHT (DihydroTestosterone) - High DHT levels cause issues (prostate cancer, acne, hair loss). Some DHT is essential for maleness (libido, body hair, etc.)
SHBG (Sex Binding Hormone Globulin) - Traps much of the circulating Testosterone and makes it unavailable to exert its effects in the body. The Testosterone left over to do the work is known as “bioavailable” Testosterone. SHBG increases with age. You want this to be low. SHBG is ordered primarily when the total testosterone results do not seem to be consistent with clinical signs, such as decreased sex drive in men
PSA (Prostate Specific Antigen) - Only a concern for those over 40 (not sure why though).
Cholesterol - Low cholesterol can mess up the steroidal hormones.
DHEA-S (Dehydroepiandrosterone Sulfate ) - Low DHEA-S can indicate adrenal problems and low DHEA can affect hormone production
Estradiol (E2) - E2 near 22pg/ml [somewhat applicable to most]: mental health, libido, prostate health, fat loss, energy, assertiveness [vs passivity], noise intolerance, irritability and social withdrawal.
LH/FSH (Lieutenizing Hormone/ Follicle Stimulating Hormone) - Low LH/FSH is known to eliminate most of the pregnenolone production in the testes, creating low levels. Low pregnenolone often leads to lower DHEA and other adrenal hormones. Pregnenolone is used in the brain to create neural steroids that are vital to proper brain functioning. FSH is shutdown on TRT + hcG and is responsible for testicular size and sperm stability - many on a FSH drug such as hmG note much improved testicular size, increase in ejaculate volume and better orgasm.
TSH (Thyroid-Stimulating Hormone) - Also known as thyrotropin. Peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland, which regulates the endocrine function of the thyroid gland.
Thyroid - Controls how quickly the body uses energy, makes proteins, and controls how sensitive the body should be to other hormones. Hyperthyroidism (overactive thyroid) and hypothyroidism (underactive thyroid) are the most common problems of the thyroid gland. Hypothyroidism may impact ability for the body to absorb transdermal testosterone (t-gels/creams)
Prolactin - Prolactin (PRL) or Luteotropic hormone (LTH) is a peptide hormone primarily associated with lactation. Prolactin has many effects including regulating lactation, orgasms, and stimulating proliferation of oligodendrocyte precursor cells. Provides the body with sexual gratification after sexual acts: The hormone counteracts the effect of dopamine, which is responsible for sexual arousal. This is thought to cause the sexual refractory period. The amount of prolactin can be an indicator for the amount of sexual satisfaction and relaxation. Unusually high amounts are suspected to be responsible for impotence and loss of libido (see hyperprolactinemia symptoms). It also decreases normal levels of sex hormones (estrogen in women and testosterone in men). Prolactin also enhances luteinizing hormone-receptors in Leydig cells, resulting in testosterone secretion which leads to spermatogenesis.
CBC (Complete Blood Count) - Used as a broad screening test to check for such disorders as anemia, infection, and many other diseases. Very common test. Many patients will have baseline CBC tests to help determine their general health status. If a patient is having symptoms such as fatigue or weakness or has an infection, inflammation, bruising, or bleeding, then the doctor may order a CBC to help diagnose the cause
CMP (Comprehensive Metabolic Profile) - Frequently ordered panel of 14 tests that gives your doctor important information about the current status of your kidneys, liver, and electrolyte and acid/base balance as well as of your blood sugar and blood proteins.
Lipid Profile - Group of tests that are often ordered together to determine risk of coronary heart disease. They are tests that have been shown to be good indicators of whether someone is likely to have a heart attack or stroke caused by blockage of blood vessels or hardening of the arteries (atherosclerois). Includes cholesterol and triglycerides.
Vitamin D-25 - 25-hydroxyvitamin D is used to determine if bone weakness, bone malformation, or abnormal metabolism of calcium (reflected by abnormal calcium, phosphorus, PTH) is occurring as a result of a deficiency or excess of vitamin D. Levels of Vitamin D3 have also shown to affect mood and energy levels.