I’m looking for some thoughts on some recent blood tests as the numbers perplex me a bit. Seeing my endo in a couple weeks- numbers below…
Symptoms low energy, low(ish) libido, weight gain and difficulty in losing weight.
The low estrogen isn’t good, it could mean your Free T isn’t high enough, your Free T converts to other hormones which is where you get estrogen via aromatization. You might have high SHBG and if so you may need more androgens to compensate. If you can’t get E2 to increase on TRT in isolation, you may need to add HCG to your TRT protocol.
Your E2 is the the ranges where I’ve seen people get diagnosed with osteoporosis. You might also have some subclinical hypothyroidism going on if TSH has anything to say about it. I recommend checking Free T4, Free T3 and Reverse T3.
You might as well get Thyroglobulin Antibodies (TgAb) and Peroxidase (TPO) antibodies while you are at it.
This is totally normal. TRT can put greater stress on thyroid and adrenals. If they are ok most likely the values will come back to normal, otherwise and if you feel symptoms thyroid and adrenals will need to be optimized as well.
Also TRT increases prolactin for most people me included
Doing labs 2 weeks after starting TRT is pointless. It’ll take a month or more before your levels reach a steady state. Do labs after 6 weeks on a consistent protocol. If you’re levels are still the same then take more testosterone.
How much Testosterone is in each injection and how often are you injecting?
When did you start TRT exactly?
How long after your previous shot did you get the labs done?
Worrying about TSH is pointless this early. See how your body responds after months before messing with anything else.
First injection was 3 weeks prior to bloods. I actually elected to get additional bloods after 3 weeks just out of interest, but I get your point. I won’t be changing anything, it’s a standard 1000mg dose of test undecanoate, only the frequency will change if required under approval from endo (every 10-14 weeks). I have another lab after 6 weeks from injection.
The low E2 is worrying, as if systemlord is right and it’s high SHBG with low free T, there’s no easy way to fix that is there? I’m not in the US and things are much stricter here, so upping the dose or adding HCG if total T is normal is probably not gonna happen…
Free T converts to estrogen, it’s not that hard to understand. I said low E2 “could” mean his Free T isn’t high enough, I see it often in men with very high SHBG, low Free T and low E2. I don’t understand why you are having a problem with it.
You know what they say, first impressions are very telling, it’s a predictor of future behavior. I’m talking about when someone joins T-Nation and uses their first post to repeatedly attack other members without offering any advice whatsoever to the thread creator.
If I remember correctly, it irritated other members as well. What I said is a real possibility and if anyone should be banned, it’s you.
That’s exactly what I’m saying, Free T converts to E2 via aromatization. Naturally you get your estrogen from two sources, within the testicles and aromatization where on TRT in isolation you only get it from aromatization.
Free T → free testosterone, it’s the active portion, the Total T is inactive.
Total T can’t convert to anything because it’s inactive, the only active portion of testosterone is Free T. You are not going to find it saying “Free T” converts to E2 because they assume you have done your homework have a grasp of the basics.
You act as if free testosterone isn’t testosterone, there is total testosterone and free testosterone in the body. When you inject testosterone, some of it gets bound to SHBG and some is active, but both are testosterone just in different forms. The free testosterone is the only one that interacts with tissue and is converted to E2 and DHT.