Blood Test In! Advice Appreciated

Please read the stickies found here: About the T Replacement Category - #2 by KSman

  • advice for new guys
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

FT is indicating a problem. But FT is pulsatile and a lab might catch highs or lows, so you really do not know the status. Normally, TT is the better indicator or T status. But in your case with high SHBG, your TT result is inflated with a high amount of SHBG+T which is not bio-available. So your T status is worst than TT=761 implies.

E2=67 is not high, so we do not expect that the liver is creating more SHBG because of that. Perhaps another estrogen [E1, E3], but that is strictly conjecture.

You cannot directly lower SHBG. Estrogens increase SHBG and T decreases SHBG.

Prolactin may be reducing LH/FSH. You really do not have a diagnosis until LS/FSH are tested and absolutely should not do anything before that is done.
Lab ranges do vary, nothing universal.

Where are you located? Affects diagnostic and treatment options.

In most USA States, you can do your own lab work. Also via LEF.

LH/FSH are not been depressed by high E2 and prolactin may be having some effect. LH/FSH can be down from damage caused by a blow to the head. Low thyroid function seems to lower LH/FSH [secondary hypogonadism]. SHBG is a major factor and low FT contributes to this. When we look for causes, we need to differentiate recent issues VS problems that have persisted for years. Sounds like your T levels may have always been lower. In that case, we can expect to see, not always, weaker facial bone structure and less facial and body hair. Some of that needs to be evaluated in the context of such traits of your father and brothers.

Your E2 is OK vs your FT, not low.

Labs:
TT
FT
E2
prolactin
LH/FSH
CBC
hematocrit
AST/ALT
fasting cholesterol
fasting glucose
TSH
fT3
fT4

You can eval overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. You can have problems caused by not using or not using enough iodized salt. LEF multi-vits will have a maintenance dose of iodine and ample selenium. How long have you used this multi-vit or similar? Any thyroid problems in your family.

I do not expect a thyroid-SHBG connection.

Have you been using any medications, Rx or OTC?
Ever used a hair loss drug?

Please provide time-line for symptoms.