Blood Pressure Increase Expectation with T Injections

Does anyone know what sort of BP increase can be expected for a middle aged man in good health (e.g. 6’, 190 pounds, good health, fit, 120/80 BP)? I’ve been repeatedly told that hemoglobin and BP will increase, though I’m having trouble getting a straight answer on what BP increase to expect. Is it 3%, 5%, 7% or other?


Subjective. It also depends on how much you are increasing your test.

For me, the higher I put my test, the higher my Bp would go when the test spiked the next day.

Im on 75mg of Losartan right now, and I keep my test at 900 on trough days.

Some guys seem to have no issues, or even have relief of higher BP. Whatever you do, don’t take Lisinopril. (increases SHBG)

It seems to affect everyone differently. I raised my test by quite a bit, but my blood pressure and hemoglobin remained normal.

This depends on a few factors.

What are your lab results and ranges for those now?

We see that hematocrit, RBC, hemoglobin are depressed with low-T and TRT restores these. So that is not a problem. While that is happening, sometimes BP can go lower because arterial muscle tone can be poor with low T. And estrogen dominance is bad for the arteries and TRT done correctly reverses that.

If blood was thin from low T, more blood needed to be moved to deliver O2 and remove CO2. So pulse can drop.

Magnesium also affects arterial muscle tone. If you get foot/leg cramps or can contract a muscle and have it lock up, you are magnesium deficient.

If low-T makes you moody, bitchy and intolerant, TRT will make you calm and relaxed and BP can be reduced if was increased by those stresses.

So you can see that simple answers are inappropriate and simple non qualified claims are highly suspect.

The idea that TRT causes heart attacks, strokes and high BP is fake news and never had any basis in fact or science. TRT increases quality of life, while decreasing cardiovascular problems. But introduction of TRT too late in life involves damage that is already done.

You will find that we try to address many aspects of health here.

If you find that your doctor makes such claims you are dealing with someone who is not keeping up with things and you may need a different doc and there is a Finding a TRT Doc sticky.

Please read the stickies found here: About the T Replacement Category - #2 by KSman

  • advice for new guys - need more info about you
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.

KSman is simply a regular member on this site. Nothing more other than highly active.

I can be a bit abrupt in my replies and recommendations. I have a lot of ground to cover as this forum has become much more active in the last two years. I can’t follow threads that go deep over time. You need to respond to all of my points and requests as soon as possible before you fall off of my radar. The worse problems are guys who ignore issues re thyroid, body temperatures, history of iodized salt. Please do not piss people off saying that lab results are normal, we need lab number and ranges.

The value that you get out of this process and forum depends on your effort and performance. The bulk of your learning is reading/studying the suggested stickies.