For reasons unknown, some metabolize T more rapidly than others.
Your T half life also reduced.
Suggest 110 mg T twice a week [220/week]. You are currently on 140mg/week.
This will get you near TT=975
This should increase E2=10 to 10*220/140 = 15.71 - some uncertainty down near E2=10
E2 target is 22pg/ml. New anastrozole dose is .25mg EOD * 15.71/22 = 0.178 mg EOD. You can’t split pills that way. Dissolve anastrozole in vodka, 1mg/ml and dispense by volume or by the drop from a dropper bottle. You respond to anastrozole more than others and your dose needs to be smaller.
E2=10 is not healthy for mind, libido or body. A change of dose takes 5-7 days to reach final serum levels in the body.
You can make both changes at once if doc will change Rx. Without change in T, you should cut anastrozole dose in half and stop for 4 days to speed up the process then resume at the lower dose.
You could change anastrozole to twice a week at time of injections. Some math required to get the dose. That way T and anastrozole doses rise and fall together. Your choice. Also, with your shorter half-life of T, you could switch to T EOD and have the simplicity of everything EOD.
How to manage EOD? You can have a EOD reminder in your computer calendar or dose on odd days of the month and make a jump at ends of months that end on an odd day, or swap to even days the next month.
In the future, try to do labs halfway between injections to reduce lab timing artifacts. Doing labs at time of office visit not a good idea.
Please read the stickies found here: About the T Replacement Category - #2 by KSman
- advice for new guys
- things that damage your hormones
- protocol for injections
- finding a TRT doc
Re your thyroid labs:
You can check overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Most common cause of low thyroid function is not using iodized salt. If temperatures are good, thyroid labs may not be needed.
If you do thyroid labs, please do TSH, fT3, fT4 [not T3, T4]
It is fT3 that is the active thyroid hormone.