T Nation

Blood Clots on TRT


Hi Guys…I haven’t been here in quite awhile. I recently got diagnosed with a blood clot in my calf. As this is my second occurance, I’m thinking this is it for TRT. Problem is, I’ve been on for 10 years starting in 2007. Had my first DVT in 2013, and my second this past weekend trip to ER. Anyone with similar experience?



How about some minor details like age, health issues etc?

Blood clots are really not seen as an issue here. Cardio vascular problems are increased with higher E2 levels. Are you managing E2 with anastrozole?

How are you feeling otherwise? Energy, libido, initiative, mood etc?

What meds are you taking, Rx and OTC?

Do you have heartburn?
Do you get leg cramps? - magnesium deficiency and has CV impact.

Labs should include CRP for general inflammory markers and homocysteine which is cardio specific.

Labs in list format with ranges please.
fasting cholesterol
fasting glucose
hematocrit [HTC]

See first suggested sticky for more info.

Please read the stickies found here: About the T Replacement Category

  • advice for new guys - need more info
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.