Better to Take AI with Injection or to Spread it Out Over the Week?

This is easy.

Anastrozole is a competitive drug, with T, and has the expected linear effects.

Target is 22pg/ml and you are at 49

New dose is 0.5mg twice a week X 49/22 = 1.11mg twice a week.
That suggests that your T dose may be closer to 200mg/week, but TT certainly does not read that way. SHBG may be lower.

Try 1.0 mg at time of injections.
Half life means that dose change delivers final serum levels in ~five days. So effect will build.
I expect that you will feel like a different guy in one week.

Please aways to labs half way between injections so that lab timing artifacts are minimized.

While both T and anastrozole serum levels will drop some in 3.5 days, they maintain a useful ratio and E2 is manage well this way. So you can stick to EOD/E2D injections.

Were these in your other threads?
Please read the stickies found here: About the T Replacement Category - #2 by KSman

  • advice for new guys
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc