If he's lifting heavy, and gets lean enough, he'll lose some strength. Saying he should do for example 3 sets of 3 for 275 and not change this if HE PHYSICALLY CANNOT do it anymore is moronic. How are you going to keep the training the exact same if you physically can't move the weight. If you get weaker, and still want to hit the reps, the weight is going to come down slightly. If you want to keep the weight, you'll have to lower the reps. This is of course assuming the OP is going under 10% bodyfat or so. It's easy enough to maintain strength when you're in higher body fat percentages but eventually as you get lean enough you're going to lose some strength.