[quote]Rusty Barbell wrote:
I have issues here…
retailboy (some other guy? BigKiwi?) wrote:
Inducing hypoglycemia by taking insulin is more complex. Hypoglycemia will deplete the body�??s glycogen stores as the body breaks down the glycogen in an effort to mobilize glucose and return blood glucose to normal. This depletion leads to decreased performance in the gym, which leads to decreased stimulation of muscle growth. I’m also a powerlifter. I’m an insulin dependant diabetic–and have been for over 20 years and I’m a doctor in a very, very specialized field of medicine. Having stable blood glucose levels the week prior to a meet is the single most important thing I have to deal with as diabetic. One episode of severe hypoglycemia will significantly affect my max lifts (ie what I’d do at the meet) for up to 3 days. So don’t take a “little low blood sugar” lightly. It�??s not just a “shaky weak feeling”.
I disagree with the assertion that stable blood glucose levels for an entire week or one severe hypo episode will significantly affect the performances of a type 1 diabetic for up to 3 days. As long as I am not taken to the hospital, the worst I can possibly experience from insulin-induced hypoglycemia is a headache that lasts a few hours after the episode as my body renormalizes itself. A 3 day effect for anything outside of going into a coma is not accurate and overstated.
Also the type 1 diabetic has not only defective insulin production, but also has defective counter-regulatory responses (glucagon, epinephrine, cortisol) to hypoglycemia and he technically should not be using himself as an example for situations to deter healthy persons from taking exogenous insulin; their body acts in vastly different manners with respect to glucose homeostasis and their response to insulin is not the same.
I also mentioned the “shaky weak” feeling several times in this post. What�??s that? It�??s a direct result of secretion of epinephrine due to low blood glucose. Remember, the body�??s goal is homeostasis. It�??s going to secrete glucagon and epinephrine in response the injected insulin as the blood glucose drops. You have to take enough insulin to overcome this homeostatic mechanism which is where things get very, very dangerous.
No the “shakes” are a direct result of low brain glucose levels. Why would epinephrine release cause you to feel “shaky and weak” if epinephrine release is supposed to be a part of the “return to normoglycemia (ie, feeling normal again because your glucose is back above 60-70 mg/dL)?”
And who said you need to take insulin use to this point to get positive growth effects anyways? Where is the evidence?
I agree that it is extremely dangerous, but we need to be properly informed and most importantly UNBIASED in our opinions before we think we can write about why the dangerous nature of insulin use and what it does is enough to deter a person without diabetes to never take it…[/quote]
True the low brain glucose levels would be there symptom but in addition the falling glucose would trigger counterregulatory hormones ie. epinephrine or adrenaline. Which would give us the tremors. And that’s where the shakes are coming from.
From what I’ve been taught neuroglycopenic sides are more like: modiness, mis judgment, weakness.
I agree using himself was bad example…
Agree as you and bushy pointed out, getting results on low dosing is ideal - away from sides he mentioned and still get the results. Also about the unbiasedness.