As the title says, my shbg is on the lowish side and I do better with EOD dosing. BUT it drives my e2 up for some reason.
I have tried lowering my test dose, but still can’t seem to dial it in as best I feel I could.
I know the ramifications of too low e2 and arimidex (thanks alpha gunner), but what would an arimidex protocol look like with an EOD protocol? Could I get by with dosing it twice a week?
I found taking an AI EOD to be too much to often especially if you are an over-responder, I would take anastrozole no more than every 3-4 days. I found aromasin to be better as its slower acting and takes 3-4 days to reach full effectiveness which makes it perfect for twice weekly dosing.
I cut up the 25mg aromasin into 1/10’s and take it twice weekly.
Going by what systemlord said, 25 mg aromasin roughly equal to 1 mg of arimidex. So start with 0.1 mg arimidex 2X per week. This is where I would start too, BTW.
How’s your body fat percentage would you estimate? Dropping body fat, improving gut health and liver health are the top 3 days you can reduce test to e conversion.
To that point, if you’re E is over the lab range you could reasonably conclude that your Free Estrogen is likewise very high. Just because you go EOD and/or use such a small amount of Cyp does not mean that you can always control E thru that method, control enough to not need an AI, I mean.
I over aromatase and have to use 12.5mg Daily of Aromasin even using just 16mg/D of Cyp. I have a theory that I have applied to myself that your E2 Sensitive should mirror your SHBG #. My SHBG is 12 at last test and I’m doing the best Ive ever done with my E2 in the single digits. If it’s affordable for you you should add a test “Estradiol, Free”, it can be an eye opener for the low SHBG guy.
As another way to look at it, SHBG binds to E, just like it does to T, which is my point about Free T being so high.