I take it and believe it should be at optimal levels. It’s cardioprotective and may be of value in treating CVD. It’s been shown to reduce the accumulation of abdominal visceral fat and protect against insulin resistance. It is being investigated as an anti-aging hormone as it blocks carcinogenesis, block aging and exerts antiproliferative properties. Low levels are linked to increased of developing cancer or of death from cardiovascular disease as low DHEA-S plasma levels are linked with an enhanced risk of cardiovascular mortality.
It decreases levels of proinflammatory cytokines interleukin 6 and TNF-alpha. It has been found to increase BMD in spine patients on treatment.