Free T ‘normal’ ranges are usually age-adjusted because Free T is dependent on both Total T and SHBG. Total T is usually not age-adjusted, but SHBG is. Personally, I think age-ajusted ranges for T and SHBG is a bunch of BS. That is, when docs interpret these ranges to say that you need to be within your age group.
Hell, I’ll be 63 years old in a few weeks. Look around you. Do you want to look and act like the ‘normal’ 63 year old man? My approach is that you need to approach TRT with the attitude of titrating your dose to where you feel your best and then I tack on to this not to exceed the upper bound of a ‘normal’ 20-30 year old guy. That part of my interpretation may be controversial in this group, but none of us have the corner on truth for TRT since there is little actual research behind modern day practices.
As it happens, I’ve done this experiment to find the optimal dose at which I feel my best and have plotted the results against Free T levels. It happens that I feel my best around the upper bound of the 20-29 year old group, so that is my target. based on participation in several forums over the last 8 years, I think a log of guys (and their docs) make two crucial mistakes with TRT:
They start at a low dose and never optimize for complete symptom abatement. I was in that camp for about the first 5 years of my TRT. Stuck around 100 mg/week in an E3D protocol. Symptoms were much improved from pre-TRT, but not optimized.
They jump to the high end of the TRT range (usually around 200 mg/week) often without their docs knowledge, because of voices in these forums. They never take the time to see if they could have the same symptom relief at a lower dose with fewer side-effects. Yes TRT does have side-effects.
Here’s a graph of a dose-response experiment I carried out on myself to optimize my TRT dose. I’ve settled on a dose somewhere between 125 and 140 mg/week in either an E3D or E2D protocol. I feel that all of my lo T symptoms are fully abated in this range and it puts me near the range of the upper bound for Free T for a 20-29 year old male. Do I feel better with higher doses? Yes, to a certain extent, but it is not symptom abatement. I feel better because I recover faster from exercise and am able to push weights and cardio to more intense levels. Is this TRT or is this anabolic steroid use? I would argue the latter (I know controversial in this forum).