I am requesting suggestions on what others might do if they were in my situation. Below you will find:
2. My questions.
3. What I am considering as my plan of action.
4. A Brief history to understand my journey thus far.
O1: Get hormones in line with those of a healthy male.
O2: Morning wood, it has been so long.
O3: Lose my spare tires. Nothing cool about a skinny guy with a gut.
Q1: What is the best way to up regulate T receptors, I have been on TRT for 8+ years? HappyDog48 provided a great write up on E2 that mentions overtime T receptors downregulate.
Q2: How do I return my ?marbles? to their number size after 8 years on Androgel w/o HCG?
Q3: Are there negative long term effects of using Adex? It looks like I am E2 dominate and might need Adex for many years.
Q4: Suggestions on how I might lose weight when I do have to motivate myself to do basic tasks like take out the garbage, etc.? I am 40 years old, 5?6?, small frame, 185lbs, 27% body fat, with most of the fat on stomach and thighs. If it is relevant, I weight 135lbs in highschool.
Q5: Where can in find information (ideally articles) on the safety of mixing DIM and Adex.
Q5a: Is there a way to tell how long it takes for my body to metabolize E2?
Q6: Am I better off taking Magnesium, Zinc, and B6 separately vs ZMA?
Q7: How might many of you modify my proposed plan (please include dosage amount, frequency of dose, and weather you would take it AM or PM)?
Q7a: Do I need to work HCG back into my plan?
Q7b: Is there a way to extend the life of HCG once mixed? It seems to not work as well after 30 days.
Q7c: HCG instruction call for mixing 10ml of solution with powder, is this the standard mix used on T-Nation for guys?
- Proposed plan:
I currently have Rx for HCG, Arimidex, and Cabergoline. My current doc is open minded; however, I like to provide medical reports to back up what I am suggesting.
0.25mg Arimidex (pill form) every day (initial Rx was 1mg everyday)
1mg Cabergoline 5 days a week (same as Rx)
300iu of HCG every other day if it will enlarge the marbles (Rx is 600iu 3x week)
1mg Vitamin C 4x day, everday
3 BodyTech ZMAs every night
1000IU Vitamin E 1day a week
2mg Copper 2x week.
- Brief History:
-2001 Prolactin (PRL) secreting growth on pituitary ID; a Men?s Health article made me suspect I had low T. I had to plead with my primary care doc to test T levels; T=mid 100s & PRL=694 (upper limit of range is 18), E2 was not tested as I was not aware to consider it.
-2001-2004 TRT with Androgel and Dostinex/Cabergoline. AI not prescribed.
2004 Dostinex did not reduce size of pituitary growth, had it surgically removed.
-2004-2006 Dostinex and Androgel due to fragments of growth still producing PRL=60 (upper limit=18); again AI was NOT prescribed.
-2007-2008 Prescribed HCG at 1200iu 3x week, no AI prescribed. For 3 months in 2007 I dosed HGC at 1200iu 3x week. Great results! Morning wood for 1st time in decades! Re-realized the beauty of women (no interests in sex at all prior), I chased any and all tail!
I could not get enough; I entertained self several times a day. T spiked to over 1100ng/dl, PRL=35 (max=18), E2=156; doc wanted my T under 800ng/dl. He worked me down to 600iu of HCG 3x week. Gradually, libido and morning wood disappeared.
-Lost work insurance in 2nd quarter 2008, I have not been on HCG since May 2008.
Used Novedex XT, ZMA, Cabergoline (I had enough to get me to the time when I had insurance again), & Vitamin C. Lab results with these over the counters and Cabergoline were: TT=1000, E2=27, PRL=12. Interestingly no libido with these numbers. I also gained 35lbs with most of it in my gut which I have not been able to get rid of.
-2009 I got insurance back. Doc stated you cannot be sure what are in these unregulated supplements, they have low quality control. We agreed to try Cabergoline and an AI (Arimidex 1mg every day for 90 days).
After 90 days: TT=540, E2=13, PRL=10. I freaked out with E2=13 and stopped taking Arimidex for 2 weeks until my next office visit. In a 2 week period my E2 increased by about 150%, PRL increased by about 40% and TT dropped by about 170% (TT=320, E2=32, PRL=24).