Your doctors don’t know what their doing, their like a chicken with their head cut off, they don’t know what to do because they just don’t understand a goddamn thing about male hormones. They don’t have the knowledge or the capability to balance your hormones, they don’t even have all the lab technology to check your E2 levels.
Your super low E2 levels are a big red flag that your testosterone levels are low for you and yet here we are still fighting with doctors.
Fear = hesitation. They would rather not risk their career and get in trouble for something they know little about. You really need a specialist who does this kind of thing for a living on a daily basis.
The NHS is not the answer, their too dysfunctional and are decades behind. Some of the logic that comes out of these doctors is laughable.
Thanks for your reply Systemlord. I know your are totally right that they don’t know much about male hormones. I honestly was not expecting much. Just hoping to get my meds and bloods via the NHS. Just going through the process on the off chance. Still really pisses me off that these doctors are failing their patients. I also pay a shit load of tax and like most in the UK pay for the “free” NHS healthcare. Many times they do a fantastic job but unfortunately there are many other times they are hopeless.
Got a reply from the NHS endo on my birthday yesterday saying he would not offer a TRT trial because my total test did not warrant it… So I’ll just keep self medicating and go to a private doc for a script. (Need that for travelling abroad)
Two injection a week given your SHBG levels, 50mg twice weekly, 250iu HCG 2-3 times or EOD, .25mg AI to start taken at time of both T injections. The test and HCG will raise your E2 quickly.
Thanks for your feedback. I am following this protocol already but leaving out the AI becuase my E2 was very low before and I’m worried about bringing it down again. I actually wanted to raise my E2 to see if that makes a difference in how I feel. Also I’m conecered about AI induced arthralgia and possible autoimmune issues. I already have an autoimmune disease which causes joint pain and would hate to add to the joint problems.
Okay some good news with regard to UK doctors. Well slightly good news anyhow…
Went to see my GP to talk about my latest bloods and to tell her how unhappy I was with the shitty endo I saw a month ago and she was very symperthetic and seemed shocked at what the endo said about low E2. (“E2 is a woman’s hormone and you don’t need to worry about it”) I told her to cancel my appointment with him next month becuase I have no confidence he knows what he is doing and the stress just makes me feel more ill. My GP then offered to try and find a hormone specialist in my local area which might take some time. I said I’d already found a good private doctor and I’d rather get moving fast and see him. She agreed that once I have a diagnosis from him and if he writes the first prescription she will take over prescribing after that. Plus she will do the bloods to monitor TRT. So It’s something positive, so I’m getting somewhere.
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I’m about 15 days since I started self medicated TRT. Would be good to get some feedback about the above question about dangers of joint damage with an AI? Also I wondered how quickly E2 can rise with the above protocol?
First week starting TRT I did not feel anything much to be honest, though I started having nocturnal erections every night. The the second week those when away. I’ve had some pain in the testes the last day or two but now seems to have gone away. I am now getting some joint pain and joints cracking more than usual. I was hoping my E2 would increase and joints would feel better but still have joint pains. Could be unrelated though, just thought I’d mention it.
I had joint pain for several months after starting TRT, you have extremely low estrogen for god knows how long, it’s going to take awhile to fully heal. Sounds like the second week of starting TRT your pituitary shut down, therefore erections are expected to go away for a time. You have seized control of your HPTA and it will take time for erections to return.
I understand that this all take time and it’s not an instant fix. I’m cool with that, just was curious if joint pain was typical for guys who just stated TRT.
Still wondering about the joint damage risks with adding the AI though. Any thoughts on that?
Thanks for your continued support. Very much appreciate it (;
My e2 dropped recently due to I think over responding to ai. I got pain in arch of a foot. I attribute this to my low E2.
Resolved quickly as I caught the low e2 with lab that was due anyway.
I don’t think ai causes joint pain. It’s the low e2 that does. Just need to keep monitoring labs until you have a smooth and dialed in protocol.
When my e2 dropped also lost penile sensitivity for a couple of days. I have since stopped ai and will see what my e2 goes to in a few weeks. I would think with no ai it should be increasing with each shot.
Well I think you are right that it’s the low E2 that’s causing the joint pain. Maybe people automatically assume it’s the AI itself, rather than the AI crashing E2… My joints have been fucked since I was 17 and I just assumed it was my autoimmune issue, but it could have just been low E2 all those years.
Quick update… would very much appreciate some feedback.
Started my TRT about five weeks ago (50mg test E every 3 days + 250iu of HCG EOD) and am still getting severe low E2 sides and feeling pretty crap. I do understand I need to be a little more patient and t levels take some time to stabilise but just had sone new bloods done and the results are surprising in that the t levels and E2 are lower than before. Anyone know why that is the case?
Your body is going through your testosterone fast, you’re most likely a hyper T metabolizer. You’re going to need a hefty dosage increase to raise testosterone and estrogen to youthful levels.
You’re still well below midrange, you need 25-30 nmol/L.
I had low E2 sides doing 40mg twice weekly and am probably still slightly low E2 at 50mg twice weekly since my erections are still soft and non-sensitive.
Thanks for the quick reply… Never heard of a testosterone fast which is interesting. I am getting regular night and morning wood which is something positive I guess. Just assumed my levels would have increased over the last month or so. One other thing to note which might make a difference to my levels is that I’ve had a virus for about three months. Can’t seem to shift it.
So what should I increase my dosing to? I’m on 100mg a week at the moment.
If your levels fall short after 6 weeks on a new protocol not much else can be expected since by this time you’ve reached a stable state. Try increasing your dosage by 70mg every 3 days and keep the HCG dosage the same, you don’t want to go changing multiple things at once otherwise results will be too dramatic. I’ve been dealing with a cough for months, it hasn’t affected my levels one bit.
On April 23 I’m pushing for a dosage increase, currently on 100mg weekly split twice weekly.
T hypermetabolizers typically need 300mg T per week to get where others are at 100mg/week. Then half-life is shortened so injections should be divided for EOD [every other day]. Subq injections are also smoother release than IM.
If free T calculates OK, you can disregard high TT. That could be from low clearance rates for SHBG+T and SHBG may also increase if E2 levels recover.
Thanks for the reply Ksman. So what would you recomend I change my weekly dose to? Should I increase slowly of jump straight to what you suggested might be required? (300mg)
Okay changed my protocol to daily injections. Wanted to see if daily worked better than EOD. Bit of a pain pinning every day but we will see… I read someone who was a hyper metaboliser switched to daily Test Prop injections and that made all the difference to him. What would be the reasoning as to why he would get on better with Test P rather than Test E or C?
I have really upped my dose because of my blood results being lower than when I was not on TRT.
Current protocol = 0.17ml (test e 250mg/100ml) ED + 250iu HCG EOD
So this works out to be 42.5 mg per day or 297.5 mg per week… Will see if my numbers improve and then consider lowering my dose a little.
Also wondered if my DHEA-S was a little low and if it might be a good idea to take a supplement to get it a little higher than low normal?
