Ask Physiolojik Thread

It has been a while since i have been on here - Hope all is going well since you moved to Colorado. If you get back to Ohio some time – If you come back to Elite FTS Sports performance summit-- maybe we could meet. These were my resutls last spring ===This was done March 2018

TSH- 2.795 (0.340-5.600 mcIU/mL)

Testosterone Total – 522 (300-890 ng/dL)
Testosterone Free – 81 (47-244 pg/mL)
Testosterone Percent Free - 1.5 (1.6-2.9%)
Sex Hormone Binding Globulin - 47 (11-80 nmol/L)
My Free was below normal – My doctor said that didnt matter.
Was 46 then - getting ready to turn 47.

I had a question – What if i was able to get some test - and do it myself. what dose would you suggest to start – how long etc. . Would you suggest taking tamoxifen as well. I would rather do it with doctor supervision but mine has no interest in helping me. Not sure where to go to find a doctor that would help.

Not pharma or trt related really as I am not on trt or ever done any cycles but had a question regarding some issues I have been having. Any thoughts would be appreciated.

Would someone with only 1 working testicle be more susceptible to huge hormonal swings? Would it make the whole system more delicate and prone to fluctuations in terms of testosterone levels?

Keep it basic. 200mg test a week and see how you feel :wink: @StormCobra84

Love love travel bro. Going to Thailand for a wedding :slight_smile:

@unreal24278

@kd13 do you have some hormone panels I can see?

Ok, Thanks man. That may be the road I take.

@StormCobra84 I’ll be in the Ohio area in spring :slight_smile:

Awesome. Sounds good. Maybe it is possible we run into each other.

Lh 3.1 iu/l
fsh 6.7 iu/l
tsh 2.1miu/l
Prolactin 200mu/l
Testosterone 19.1 nmol/l ref (8-27)

I know these may not be all that useful but they are the only ones I have from when the fertility specialists wanted to check for evidence of sperm production before a surgical sperm retrieval. (Damaged vas)

90% of the time I feel amazing, great mood and energy, raging sex drive and non stop erections. At 32 I feel like a 16 year old. But then every now and again I seem to go through a very short down period with missing morning wood and low mood and irritability (still have raging sex drive though) which may last only a week or so before returning to my normal self. It seems to follow a distinct pattern, like I have a peak and then fall off. It only happens every few months.

Not really sure what’s going on or if the 1 testicle could be an issue. Thanks for any insight.

1.i’ve been on TRT for 2 years (85mg test-e twice/week), have done 2 blasts with 440mg/500mg test e/week for 16 weeks each. results were underwhelming, do you think this is due to the fact that my body is already used to external T at a good/high level?

2.Would you recommend stacking something else (only “mild things” would be an option, I’m not looking to get on stage, just adding about 10 more pounds of lean muscle) like MK-677 or just go higher with test-e?
tren is not an option, boldenone/EQ (afraid of heart/hermatocrit issues) and deca (prolactine, also I might come off completly in the future to try to have kids) are also not that appealing…

3.Do you think it would make sense to go completly off (even of TRT) for a few months, in order do “clear” the receptors? the months would be hell, and I would for sure lose a bit of size, but would it be worth it because the response afterwards would be much better when I’m doing my next blast from 0 then from just cruising at my TRT dose?

  1. All my bloods are still good, only thing that got significantly worse is HDL. Started at 70, now down to 41 (reference says it should be >45). At the same time my total cholesterol has gone down also from 210 to 155, so the ratio CHOL/HDL is 3,8 and still okay I assume, my doctors was fine with hit.
    Interestingly the big fall down from HDL 61 to 41 and also total cholesterol from 200 to 155 was during 3 months this summer where I was slowly tapering down from 500mg/week to 170mg/week… What would you suggest to do about HDL?

This isn’t my thread, and I probably shouldn’t be poking around answering questions not directed at me but I felt like I might be able to help.

Unlikely, 170mg to 440-500mg is a very large difference, 170mg isn’t even THAAT high for TRT, I’m gonna be cruising on 200mg for 8-10 months once I’m done my mini blast before I do anything again, 200mg is what I would call a high TRT dose. The reason for underwhelming results could be related to various factors, I’ll list some of them

  • Training/ diet, a subpar diet and training routine with gear will only take you so far, to truly get the most out of it you need to train like a beast and eat like a beast, AAS aren’t a magic pill (although they’re pretty magical)
  • Individual drug responses, the amount of muscle mass one will put on from anabolic steroids (at what dose, how much they put on etc) is largely up to genetics and how long one has been training for, if you’ve been training for 20+ yrs and you’re at your genetic limit, you can’t expect to get the same results as some moron (like me) who isn’t close to their genetic limit… unless I had a really shit response to drugs and you had a Kevin Levrone style response.
  • Was the gear pharm grade or UGL, sometimes UGL’s can be underdosed, that’s why it’s essential to look up reviews on said UGL before using their gear, and even this isn’t foolproof, exit scams, shitty batches and whatnot are always a possibility

Not enough research to determine the safety level of MK677, and MK677 isn’t a SARM, nor is it a peptide, it’s a Ghrelin receptor agonist, there is concern as to how it may affect the ability for people to adapt to stress… however it’s based on one rat study. Anabolic steroids have been hypothesized to be neurotoxic at high concentration, this hypothesis can further be pressed by the findings of structural differences in the brains of AAS users compared to non users, however the studies are small and many were involved in recreational hard drug use, however when factoring out the drug use AAS induced structural changes were still apparent, these changes couldn’t be distinguished by a change in behavior, depression or whatnot. However one study found long term AAS use to impact visuospacial cognitive function, while others didn’t. Anyhow what I’m saying is, I’d stay away from MK677 until more research verifying the safety of the compound is out.

Deca is probably more likely to cause heart issues than EQ, to control hematocrit you can donate blood or opt for therapeutic phlebotomy, not telling you to use EQ, just saying there’s a way around

From a health point of view, no, not worth it. the clearing receptors… Sounds brosciency, if you’ve been on TRT doses for long enough post blast your body should be at a point of homeostasis, blasting again will be exposing your body to new stimulus, so what’s the point of going off… Other than feeling like shit.

Anabolic steroids, even test at supraphysiologic doses, will almost always exert a negative effect on HDL cholesterol and potentially LDL, but for test not usually if one is careful and the dose is sane (for LDL). The extent of negative effect is largely up to genetics, some people can take winny and maintain a good lipid profile and others take test and their HDL drops below 40. Anything above 40 is technically normal so don’t worry, what’s your LDL? Supplements that can help cholesterol are NAC, COQ10, a healthy diet, regular cardiovascular exercise, niacin if you want to simulate menopause (with regards to hot flushes, it’s super fun).

yeet, hope this helps in some way

@physioLojik

I have this huge bottle of 1-andro (DHEA isomer 1-dehydroepiandrosterone), seriously a ton of it. Im wondering if there’s any benefit to trying it for a few wks, say after my mini blast is over but before I get my bloods. There’s a tiny paper quoting its effectiveness, it appears far more risky than regular DHEA, however a small paper indicates it may have some anabolic effect. Honestly I’m just bored, I have it and I’m wondering if I’m ever going to use it or if it’s a waste of 200+ dollars (got it when I was put on trt, but never used it… I probably have enough to use it for 6 months if I wanted to, but I don’t want to use it for that long, I’m just pondering what to do with it and I’m curious if it does anything or if it’s BS. I’m actually thinking of throwing out my NPP, no use for it, nor do I ever think I’ll need it in the future

It’s dumb but I figure “it’s a DHEA isomer, highly doubt it’s going to do that much harm”, question is, is it worth it or do I just chuck it. It converts to similar metabolites, however instead of the end goal being testosterone it’s dihydroboldenone, and instead of a first conversion to androstenediol or androstenedione it’s 1-androstenedione/ 1-androstenediol.

I don’t intend to cycle again after this for a while, as in probably not for another 8 months or more, not sure why im putting this in here as it’s not important though. I’ll just cruise on 200mg of test. I think with my doses and minimal to no time on vastly supraphysiologic doses and my decently healthy lifestyle becides my alcohol consumption which clocks in at one or two beers a week, except for recently where I’ve stopped drinking beer due to the GI index of it, so now zero drinks with occasional times where I get mildly intoxicated, say once every three to four months or so, I can really minimise harm done and live a long and healthy life provided I don’t get hit by a bus walking down the street or get cancer or suddenly die from sudden cardiac death for absolutely no reason or something.

So question is, is it worth a shot?

hi unreal,
I appreciate your input and willigness to help, however, I’d like @physioLojik to answer my questions, this is why I posted them up in this thread.
He has a lot more practical experience, this is what I’m looking for, you on the other hand just provide theoretical knowledge of studies (which I’ve also researched heavily) and your personal VERY limited practical experience.
E.g. I’ve read every study on MK (there have been some human studies as well mate), there won’t be any more since it has been stopped developing to my knowledge and will never be a FDA approved drug.
In terms of training&diet - I’ve been in the game for 11 years now, came pretty close to my natural limit (6feet, 180lbs, 10%bf, bench 260, DL 405) before I started TRT 2 years ago, so I’d say I know what I’m doing, at least as a natural guy.
Of course my gear is legit mate, its straight from the pharmacy, same stuff I use for TRT.

Yeet, sorry about that I get very bored sometimes, wasn’t my place to respond

Why did they stop developing it? This is a legit question I’m curious

Do you get 500mg prescribed? If so, that’s awesome, how do all these people get this stuff prescribed lol. I’d kill for that. (Not literally)

@john_german @unreal24278 hey there guys. John I can tell you that even without experience everything @unreal24278 said is pretty much right on point.

@unreal24278 I wouldn’t mess with that stuff you have. Just manipulate your test dosage.

Yea I guess I’ll stay away from it (the 1 dhea), I’m not going to manipulate my test dosage though, 250mg/wk is already the most I’ve ever used (the amount I’m currently using), and I’m making nice progress, plus I’m not entirely comfortable going higher. I have to come off in time for bloods, however I could always switch to short estered T before bloods, eh, why bother, prescribed TRT dose is currently 140mg/wk so it isn’t as if I’m going to lose any gains going from 250-140 then back up to 200 for a long period of time, esp if diet and training is good, I’ll continue to make gainzzzz

alldayeveryday

5d

@physioLojik, if a guy is in a tight spot and doesn’t have access to pharma grade tamoxifen… can RC sites tamoxifen be used?

I’ve used RC products alot. Mostly because turnaround time is short and a lot of UGLs have minimums and I dont need to spend a lot just to get some Nolva or whatever.

I’ve had great results with RC letrozole in killing some pea sized gyno. I know a great website but I can’t share due to the rules.

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