Low free t = risk factor for high grade prostate cancer
Results here. Quoted.
Overall, Towe’s study included 830 consecutive patients presenting to a single surgeon’s practice for management of local prostate cancer. Correlation between total and free testosterone were compared with clinicodemographic of age, preoperative PSA, prostate volume, pathologic grade, and pathologic stage. The study team that patients with free testosterone (FT) level in the lowest quartile (<4.42 nd/dL) had the highest proportion (15.6%) of very high risk (i.e. Gleason grade group 5) prostate cancer. Compared to those with high free testosterone, this was a statistically significant difference.