If and only if estrogen levels are really at the high end,
Arimidex might help somewhat (not at all spectacularly)
with fat loss for “chubby people.” For those cutting up
to contest condition, then estrogen can be a worse enemy
BUT even so, many, many pro bb’ers have cut up to ribbons
while having higher estrogen levels than Dolly Parton
(due to aromatizing steroids.)
I don’t really have good information on whether Metformin
really helps non-diabetics or is really not useful.
I could only repeat opinions of others rather than give
facts or observations.
I don’t know exactly what the fat set-point theory is:
if you mean the theory that the body has a tendency to
return to some set point of bf, I personally think that
is somewhat true but this setpoint can change with time.
In other words, if you slowly work your way down to 8%
and keep yourself for a year, nope, your body will not
be screaming with desire to return to 20% or anything
like that. Whereas if you do a crash diet, right after
the diet the body may indeed want to get back to where
it recently was before the diet. So in that sense the
theory is true I think. Personal opinion only, another
question I do not have facts on.