Yes, applies to larger doses. Do not have data for BB dosing because we do not have labs for those guys.
When and how to take? Depends on how you inject T. If injecting twice a week, take anastrozole then. Will not work well with weekly injections. Some do EOD T+hCG +AI. With hCG working well at EOD, that can drive a routine for the trio.
If looking at 500mg T, please do labs and share results of E2 lab work and dosing here.