I work the opposite. If I stop drinking milk or eating Mcdonalds, when I go back to it, I can make bathrooms disappear. So I try to make sure at least once a week I drink a glass of milk or eat some mcd's.
I have seen people who eat too much shellfish get allergies. And I do cycle my supplements. Haven't seen any medical advice on the subject, but it's just hard for me to believe that if normally I would get 1 mg of Vitamin E from my diet that 10000 would be healthy.
The only conflict comes with lifting weights. I lift because I enjoy it and I like getting stronger. This process requires a diet that may be slightly different than an optimal health diet. With that I believe that the amount of supplement build up your body stores, is probably related to how much you excrete through diet and exercise or use in the building process. If it's leaving your body at a faster rate, you may not have to cycle your supplements. On the other hand if its an overload, then you should probably take some time off here and there.
Remember caffeine is great but the effects get weaker if used too much.