I came accross this thread from KSman in the “over 35 lifter” forum. Interesting as this concerns a supplier many of us use.
Good post thanks
Just checked my bottle. My bottle is about 6 months old. There are a few tiny crystals on the bottom. I guess the size ranging from “large to tiny” is subjective but mine are smaller than the head of a pin (maybe that is large in terms of crystal size since they can be seen with the naked eye, I don’t know I don’t have enough experience in chemistry labs to know the jargon).
Interestingly enough I have been using less Adex than I usually do. Normally for 500mg/wk T I will use .25mg EOD and that will work well. 750mg T I will use .25mg ED- .5mg E3D. Currently on 500mg T + 300mg Nand + 210mg dbol and am using less than .25mg EOD (its coming out to about 3 drops)
I have no explanation, but I am confident in my ability to manipulate my estrogen level with the use of Adex. Hopefully the company did not increase the concentration without advertising that fact (I doubt that is the case, would be uncharacteristic of the company).
A blood test would be rather pointless because I do not have a blood test to compare it to using a different product.
You can still do an E2 lab to find out where you are and reduce if needed. I assume that you are now going by how you feel.
Your adex needs are very low. Perhaps you are one of the few anastrozole over-responders who need 1/4th - 1/8th of the expected dose.
[quote]KSman wrote:
You can still do an E2 lab to find out where you are and reduce if needed. I assume that you are now going by how you feel.
Your adex needs are very low. Perhaps you are one of the few anastrozole over-responders who need 1/4th - 1/8th of the expected dose.[/quote]
Yes I am going by how I feel. After 3 runs with different doses of testosterone, or some combination of T and dbol I am confident with my ability to manipulate my E2 levels to keep myself comfortable (phyically and mentally).
You are probably right about over responding. The first time I did a cycle I followed the advice to not use adex until I felt the need to. I wound up adding it in the 6th week of 8 week 500mg/wk cycle solely to affect bloating. Maybe that means that I just don’t convert T to estrogen at as high a rate as other men. I’m not sure.
I looked at into my bottle and sure enough there are smallish crystals on the bottom. I unlike Bonez have been using more Adex than I did in the past. I have been using 0.5mg/d with 700mg/w of test e. That amount has had my libido in great shape with no bloat to speak of. I am sure if I heated it up, the dose would be too high. I am planning on adding 30mg/d dbol into the mix and had planned to up Adex to 0.75mg/d.
If anyone had an alternative source that they have been happy with, please PM me.
Is this the One many here use?
I find that their products do crystalise - i believe, due to the taste, that their products are solutions NOT suspensions, and that is why a good shake is needed.
Funnily enough, i prefered AS to CO as while the AS stuff tastes like shit, it is a real suspension, and 20ml lasts ages.
Higher cost, better product IMO.
[quote] Brook wrote:
Is this the One many here use?
I find that their products do crystalise - i believe, due to the taste, that their products are solutions NOT suspensions, and that is why a good shake is needed.
Funnily enough, i prefered AS to CO as while the AS stuff tastes like shit, it is a real suspension, and 20ml lasts ages.
Higher cost, better product IMO.
[/quote]
I have adex from CO and its doing it also. can you pm me plz
[quote] Brook wrote:
Is this the One many here use?
I find that their products do crystalise - i believe, due to the taste, that their products are solutions NOT suspensions, and that is why a good shake is needed.
Funnily enough, i prefered AS to CO as while the AS stuff tastes like shit, it is a real suspension, and 20ml lasts ages.
Higher cost, better product IMO.
[/quote]
Yes Brook. Can you PM or email me exactly who AS refers to. I think I know, just want to double check. It comes in 20ml sachets right?
Is “adex” Anastrozole or Tamoxifen?? If it’s Anastrozole like I figure by the dosage… I have a question about it in the pill form. Is it unheard of for it to be marketed in the pill form? Is it normal?? What are the pros/cons of liquid vs. pill?? Bump
[quote]mgern527 wrote:
Is “adex” Anastrozole or Tamoxifen?? If it’s Anastrozole like I figure by the dosage… I have a question about it in the pill form. Is it unheard of for it to be marketed in the pill form? Is it normal?? What are the pros/cons of liquid vs. pill?? Bump[/quote]
Adex = arimidex = anastrozole (and Tamoxifen = nolva = nolvadex)
Anastrozole is in fact, the name for the pharmaceutical product, so yes, it’s certainly available as tabs. A high quality, human grade product should be made under more stringent conditions than a research chemical product. The main trade off is higher price, and perhaps the fact that it can be harder to split dose size if required.
With CO, their products are not dissolved in Alcohol/PEG 300 as they should be, they are in a sweet water preparation… this means that they simply put (for example) 60mg of anastrozole in 60ml of the sweet liquid and expect it to be shaken… i think this makes it a solution rather than a suspension.
Most oral drugs we use are dissolvable either in grain or overproof alcohol or a mix of alcohol and PEG. This way dosing is exact and the product is a true liquid. With CO this is not the case.
They have good customer service, and are reasonably priced - they taste good too, but they are not properly made IME. I have used their letro, cialis and Adex.
I needed to dose 0.75mg of adex a day (probably not too far off what i would have needed with that particular cycle), 40mg of cialis (10-20mg over the dose i respond to best) and their letro was worthless(they replaced it with the anastrozole). I know how much powder 60mg is, (it is minute) and i know that simply adding it to a non-dissolvable liquid isnt enough to ensure even dosing.
Lastly i suspect that the crystallization of their liquid is the sugar additive, not the drug in it. 60mg is such a tiny amount, only a minute crystal would form - if it did at all.
Brook
I have a bottle of CO letrozole that worked good at first, but gradually seemed to degrade over time. And yes, there was the crystallization apparent in the ring at the bottom of the bottle that we are all noting. I could get everything to go back into suspension (or solution or whatever it is in this case) using hot water and a good shake, but I think that something had been happening for long enough that I was no longer getting an effective dose out of the amount I was supposed to take.
Either the letrozole itself had degraded or I had “used up” a lot of the letrozole somehow. I can attest to this being more than just supposition on my part in that I ordered another bottle of letro from the Guys because I was not able to get a handle on some gyno from the letro from CO (you know you have a problem when letro is not taking care of it!).
Anyway, the letro from the Guys has a taste that is pretty well emetic, but it does exactly what it is supposed to do. I have not used it for long enough to make an assessment as to how well it holds up over time, but my general rule of thumb for myself now is, the worse a research chemical tastes, the more likely it is to be effective. I don’t want a bunch of sweeteners and pretty pink coloring in my letrozole, I want something that is going to control estrogen and keep the gyno away!
That said, it may have nothing at all to do with the sweeteners and such. I’m not familiar with all of the various methods of preparation of these chemicals, and one seems quite different from the next. If someone does make a chem that both tastes pleasant and holds up until I’m done with it, I’ll be just as happy to purchase that one.
[quote] Brook wrote:
Lastly i suspect that the crystallization of their liquid is the sugar additive, not the drug in it. 60mg is such a tiny amount, only a minute crystal would form - if it did at all.
Brook[/quote]
The crystals, yes a tiny amount, that form on the bottom of the bottle are not water soluble. When I checked old bottles that I had washed and set aside, there were crystals still there. I retreaved that material with alcohol [vodka].
[quote]KSman wrote:
Brook wrote:
Lastly i suspect that the crystallization of their liquid is the sugar additive, not the drug in it. 60mg is such a tiny amount, only a minute crystal would form - if it did at all.
Brook
The crystals, yes a tiny amount, that form on the bottom of the bottle are not water soluble. When I checked old bottles that I had washed and set aside, there were crystals still there. I retreaved that material with alcohol [vodka].[/quote]
So do you think that it is likely the drug then, and not the sugar crap? Sounds like it may very well be by your description… 
My adex wasnt too bad for crystalization - the cialis and letro were much worse IIRC… I know that when alcohol is used - there is zero crystalization at all… just potent alcoholic drug preparations!
B