If one watches the anabolic doc’s YouTube channel he states trenbolone + winstrol is the combination that induces heart disease/plaque build-up at absolutely unprecedented rates. Trenbolone hits lipids hard, there are plenty of anecdotal bloods posted up online with LDL 250+ HDL <20. I don’t watch much of his content nowadays as it’s too “brosciency”, but it’s a decent source for information regarding various compounds and associated side effects.
Stanozolol is probably the harshest compound out there in terms of lipid demolition (actually methyldrostanolone might be worse, chlorodehydromethyltestosterone/and non-aromatising c17-aa AAS trailing closely). A tren/winny combo is typically a combo wherein the risk heavily, heavily outweighs the reward.
From looking at literature the effect in relation to 19-nors/progesterone/androgen mediated dopaminergiic signalling is also of concern. Trenbolone (and all AAS) are probably neurodegenerative when used over long swathes of time (I can link data and list mechanisms to prove my point if anyone wishes to rebut this). Trenbolone in particular has a unique habit of taking relatively normal men and turning them into absolute assholes/changing their demeanour completely. Reminds me of the amateur PL who was running 1-2g tren/wk (permablasting). He/his posts…. Seriously changed while he was on… and he never really came off. This effect is largely individualistic in nature, trenbolone appears to effect men unpredictably.
Look out for that… esp the paranoia/jealously that some occasionally report on tren. Don’t let gear ruin relationships with others
I don’t have any input regarding how to stack drugs like stanozolol or trenbolone as I’ve never used them. If I had to make a recommendation, I’d say drop the winny… tren is harsh enough on it’s own.
It’s a classical example of “the pot calling the kettle black”. The sheer audacity to call him retarded…