Hey coach, Pharmacist here, huge fan of your no nonsense approach to lifting… I typically recommend your work and CT’s to most guys who ask me a thing or two about lifting weights. Can’t go wrong.
That said, that “ketosis is king in the event of metabolic disease” line really bugged me. Your audience (and it is pretty wide) and their families might do the exact opposite of what their disease would require them to do. IMHO the keto-friendly crowds should ask themselves the following questions:
what kind of way of eating were they on before going keto? Frankly, the half-conscious American Diet is usually void of nutrients and high in some carbs (mostly starches = pure glucose), while limiting fruits because of all the confusion around Sugar, and typically a hefty blend of IIFYM strategies leading to some moderate fat - moderate carb mix. According to Randle et al. back in the 60s when he put out the Randle cycle (and that cycle has never been disproven) the same way hyperglycemia and insulin are pretty much inhibiting fat oxidation, elevated fatty acids inhibit glucose oxidation. Thus there could be two kings here: very low carb ketogenic diets, and very low fat diets.
the truly low-fat crowd has been publishing impressive in-patient data for decades, whereas low carb diets consistently fail over the long run. Atkins warned against the dangers of his own diet. Epileptic kids weren’t free from seizures at all, and their diet was extreme anyway. Doctors like Swank, Esselstyn, Kempner, Greger, McDougall, Ornish, Campbell, Kahn… could clearly go ahead and claim that their low fat whole food mostly-if-not-all plant diets are Ace (if Keto is still king)
I’m going to suggest a decent read from a Doc I agree with on that matter, who has a decent, measured stance.
I’m aware that you’re extremely busy so let’s just grab the sources regarding ketosis and cancer:
Titles speak for themselves… The keto rabbithole is immensely deep and embracing maximal caution is warranted. Especially when we’re discussing cancer.
We have very limited data proving any specific benefit from ketogenic diets vs Metabolic syndrome, most subjects who lose weight improve their condition anyway. On a ketogenic diet, LDL consistently goes up, as thyroid function goes down. What should we do from such “adaptations”. What about potentially clogging arteries? Pictures can be worth a thousand words when it comes to high fat diets v low fat diets and blood flow.
Photos around 3:00 on that video. Greger is notorious for being heavily biased, however I’d at least recommend to keto enthusiasts that they regularly meet their cardiologist on such a diet and perform proper imagery.
Hopefully that helps some here.