42 Y/O Recently on Cypionate and Feeling Numb Downstairs Now

Hi Everyone,

Im new to THT and happy I came across this informative site!
I need help. Im a 42 year old male. About 20 pounds over weight. Always had low T(390), but never symptomatic.Moderate Libido,energy, busy active lifestyle. About 2 months ago I started feeling very tired all the time and little libido. I went to see my doctor who ordered a blood test. A week later, he called me in to review my blood results. My Testosterone level was at 319 ng/dl L. He recommended putting me on THT right away.
He is a young open minded male doctor who sees a lot of older people in my retirement community. I really lucked out after reading some of T nation member’s nightmare experience with stubborn doctors.
Anyway, He gave me the option of either cream or injection, I picked injection, so he administered 200 mg of Cypionate IM. He wanted to see how it would work for a month and go from there.
I felt great for the first week. I got tested after my first week. My T,serum 940, Free T 21.1
Week 2, T serum 232, Free T 5.80, % of Free T 2.50.
I was feeling miserable and begged the medical office receptionist to get me in sooner with the dr.
Was seen at week 3 since previous Cypionate injection, was given another 200mg of Cypionate.
Its been one full week since my second dose of Cypionate and although my energy level is getting better, I still have zero libido, no morning erection, nor spontaneous erection and penis is numb. What is going on?
I have an appointment with my doctor tomorrow, but I though I could pick some brains on here to be better prepared for when I see him tomorrow morning. By the way, my TSH is at 2.06 uiU/ML, FSH 3.5 mIU/ml, LH 2.5 mIU/ml. Im missing my E2. Will order that test next.
Any feedback would be much appreciated!!

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While I am just starting injections myself after using Testopel for a while, everything I have read is that injecting more often is better. If I read your post correct, you are injecting every two weeks. Most people go once a week or half dose every 3.5 days to help even out the peaks.

You do not have enough tests done to really be sure but. If I took 200 mg of Test Cypionate in one shot my E2 would be through the roof Three weeks between shot is crazy your T levels were far lower than when you started by then and E2 was probably pretty high. Testosterone Cypionate has a half life of 8days. In two weeks you are close to zero. And unless you like riding a hormonal roller coaster one a week is the longest you should go, with twice a week being better.

You really need to educate your doctor or

Read this stuff

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When you read all that you will see that your doctor gave you a periodical that was never going to work. In the link below you will see a periodical that does work and get a good idea what was wrong with you

TRT: Protocol for Injections

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Ive had two injections so far.
200 ml of Cypionate IM 4 weeks ago
200ml of Cypionate IM 1 week ago

Your Dr doesnt know what hes doing when it comes to this. You feel exactly how you should after that protocol. Read everything that @verne posted and you will see why.

when you injects Testosterone your body shuts down it’s own production. 200mg in one shot it one hell of a lot. Your body will convert a lot of that extra testosterone to estrogen. After one week your testosterone level plummets below what it was before and keeps going down maybe to zero. Estrogen leaves your body slower so now you are high E2 extremely low testosterone. You very likely feel like shit and cry a lot.


Ask for this exactly, provide in writing, do not do verbal as doc can derail conversation at the beginning.

  • Self inject 50mg T cyp twice a week. SC not IM, #29 1/2" 0.5ml insulin syringes
  • 0.5 mg anastrozole at time of injections
  • 250iu hCG SC EOD/E2D with above syringe or #31 5/16" 0.3-0.5ml

Inject T and hCG SC/SQ in skin over upper legs. Pinch up skin and inject into end of fold with needle parallel to muscles below. Select injection site avoiding veins. Press on location to mark with the syringe end cap that covers plunger end, or something similar. Clean the location with alcohol prep pad and then inject there. [This avoid issue of not clearly knowing where the cleaned skin area was.] You can try belly skin as well to see if more comfortable for you.

Objective is steady T levels allowing for proper use of competitive aromatase inhibitor anastrozole to modulate T–>E2 production. Objective is high-normal TT and FT and E2 near E2=22pg/ml - 80 pmol/L. hCG preserves testes that otherwise will shrink and atrophy. Also preserved fertility for younger men.


Please read the stickies found here: About the T Replacement Category - #2 by KSman

  • advice for new guys
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.

Thanks Verne,KSman. I printed it out some general info for him… He was honest with me,
said there was zero training of this in residency. I like him and he wants to work with me but wants to take things slow before changing frequency/dosage. But that medical office is so affordable and accept my insurance, $23 an injection!
Where I live, the hormone replacement doctors with experiece, charge an arm and a leg, do not except insurance and want to use their own labs and force you to use their compounded $$$$ drugs.
They are wanting to charge around $250 for first consultation followed by $1000 a year for follow ups and “close monitoring”!

Almost forgot, was given rx for Viagra.

Does your insurance cover TRT, with TT of 390?

Hi Ksman, should the needle be parallel or perpindicular to the muscle? How important is pinching the skin? Thanks!

High pull,

my level was 319 and insurance did cover