Your low SHBG can also be a symptom of diabetes.
Low SHBG means more of your T is free T, but that will still be low in absolute terms. In that context, free androgen index is rather meaningless.
Your E2 [estradiol] = 95 is not great. We target E2=80 when TRT guys have high T levels. If you increase T levels, E2 can only go up. This means that E2 can be too high for your when on TRT. With low TT, FT we expect E2 to be low as there is little FT for FT–>E2. Liver clearance of E2 might be impaired. Do you have AST/ALT labs? Some drugs, Rx and OTC can interfere with E2 clearance.
Prolactin was low, now high. Keep tracking this. Concern is prolactin secreting pituitary adinoma and they cancelled the MRI to check for that. If serious, prolactin can get very high. Prolactin can be elevated and affecting lab results from recent orgasm, cuddling babies, puppies or kittens. So abstain for next labs.
Your T is very low. If self-injecting, inject 50mg SC/SQ, not IM, twice a week. Use #29 1/2" 0.5ml insulin syringes. Or inject EOD - see below
Do labs always halfway between injections.
You may be a testosterone hypermetabolizer. Such guys typically need 300mg T per week to get where others are in 100mg per week. And effective half-life is shortened and injections should be EOD [every other day]. Doctors do not know this and it is not in the literature.
Low thyroid function can affect glucose levels and insulin sensitivity.
Do you use iodized salt and/or vitamins that list iodine+selenium? [YES}
See last paragraph in this post!
Low T also affects insulin sensitivity.
Please read the stickies found here: About the T Replacement Category - #2 by KSman
- advice for new guys
- things that damage your hormones
- protocol for injections
- finding a TRT doc
Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.