Wish I had my original labs from prior to starting TRT but I don’t have a copy. I know total T was 209, free was 4 and change, E2 was 34 (range 7.6 - 42.6). Started TRT at 140 mg test cyp per week, single dose. I’m using a T clinic that requires you to go in for shots and at $40 a pop it adds up. Anyway, I felt amazing during weeks 3 and 4 of TRT. Then things started getting crappy again. Morning and REM wood are fine (wakes me up occasionally, in fact) but now there’s brain fog, bad mood, and all of a sudden I couldn’t ejaculate without a lot of manual intervention. That got worse and now I can only get off once a day at most and orgasms kinda suck when I finally get there. If I try to go a second time in the same day, I’ll feel the beginning of the buildup to an orgasm and boom, it’s gone, and my junk falls asleep. Feels like all sensitivity has gone. Even with low T I could go multiple times a day with no issues whatsoever. Went back for my 6 weeks labs and they are as follows:
Total T: 492 (350 - 1000 ng/dL)
Free T: 12 ng/dL
Bioavailable T: 282 ng/dL
E2: 44.5 pg/mL (high) (7.6 - 42.6) Roche ECLIA methodology
SHBG: 25 nmol/L (16.5 - 55.9)
Hemoglobin: 15.7 g/dL (13.0 - 17.7)
Hematocrit: 47.5 (37.5 - 51.0)
No lab for prolactin, which is disappointing, because I’m wondering if that + E2 or that alone are the cause of my sexual issues.
Clinic told me that they like to keep E2 below 60, even though above 42.6 is considered high, but since I’m symptomatic they prescribed 0.5 mg Arimidex to be taken 48 hours after my shot once per week. They also increased the test cyp dose to 160 mg/week because they want to get me to 600 - 800 ng/dL at trough. I know dosing test cyp twice a week (or more) would be ideal but isn’t an option for me. That said, should I do AI in a single weekly dose as the clinic said or should I split it in to 0.25 mg doses two days after the shot and 3.5 days after that? Is 0.5 mg a week even appropriate for the test cyp dose I’m on and with the last E2 lab result? Last thing I want to do is crash my E2 and all of the reading I’ve done shows a lot of contradictory opinions. Looking for input.