Have you read the following stickies?
http://tnation.T-Nation.com/free_online_forum/sports_training_performance_bodybuilding_trt/trt_protocol_for_injections
Transdermals can be very inconsistent and problematic. Since you’ve used injectables before why not try that again?
Any decent protocol should include HCG and an AI like Anastrozole, preferably from the get go (read the stickies why). If you didn’t do that while injecting that could be related to feeling crap on injectables. (HCG should especially help with mood)
You didn’t say much about your lifestyle but anxiety and PVC’s suck, so here’s my 2 cents. Get on a low carb/ keto diet and eliminate most sugars (it may take as much as 8 weeks or so to get used to so hang in there). This can have a profound effect on energy and mood (make sure to eat enough healthy saturated fats to make up for the carb loss). Get on a good, strength based, weight lifting program. Do not add a shitload of metabolic conditioning type exercises in your program (so no crossfit) because that’ll fuck with your diet (you would need more carbs for that which could mess with your mood and heart, so no metcon for now). Add some mild cardio 3-5 times a week, just a brisk walk type thing for 30 min. You can sweat a bit but no panting. This can really help with your PVC’s and likely makes a difference added to a strength based program (strength training alone can actually trigger or increase PVC’s in some people so add the mild cardio) (again, keep the cardio mild, you do not want to get in a hormonal “flight” state)
Eliminate stimulants from your diet for now. Chocolate is a notorious trigger for PVC’s so, sorry, no more chocolate. You can reintroduce things slowly after a few months and see what the effect is (one thing at a time). If you really can’t live without any stimulants try some guarana in stead of caffeine, or try some Spike or (non-caffeinated) Brain Candy. Z-12 can help with anxiety but in my experience (and my wife’s as well) only try to use that strategically once or twice a week (more often can actually backfire and cause some feelings of anxiety, so you could experiment a bit with that and see how you respond). ZMA can help you sleep. If you’re an anxious person you’ll probably sweat more and lose more minerals that way so ZMA can really make a difference for that. (and too much sweating can also mess with your transdermals btw)
Good luck