35mg of Cialis Stopped Working for Me

Did you check your hormonal panel?

This seems to be my issue too. Which is why I am always frustrated at these high vs low E2 debates. Thats all that it comes down to in most debates is how much do you convert. What if though our problem is just being really sensitive to E2 where even the upper normal range alrady gives us all sorts of problems. I have tried everything under the sun and I cant seem to tolerate higher end E2 let alone “high”.

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Yes, Testosterone 290 E2 59, very low T/E2 ratio.

How old are you?

I am 33 now my ED started when I was 23 or maybe earlier

:love_you_gesture:

Thank you for this. This comment motivated me to post here:

Bro I have had serious issues in the past with my BP and heart palpitations when I let E2 run rampant, and the longer I tried to “tough through it” the worse it got including my damn head starting to pulsate.

I am also now hypothesizing about “over responders” in general, rethinking of what that means. For me the options have always been to either lower my dose or add an AI, as from all my blood work I seemed to prefer lower end E2, erections even prove this. Even though higher doses with AI felt better than not, it was a slippery slope playing with AIs and not crashing E2, and I admit there were times where maybe the T itself was too high due to HCT or I don’t know.

So now back to “over responders” and what I am starting to think is moving away from thinking of guys who take a small dose and have high levels, but rather how your body responds to those levels. What if for some of us at 700/25 is comparable to what others here experience at levels of 1200/50? And I mean to say libido, erections, confidence, even athletic performance and/or muscle building. I been on 140mg for close to a year now, after starting TRT March 2020. I promise I don’t mean to sound like a douche but so many people have already asked me if I am doing a full on cycle and “what do you take, how much do you take, etc”. So maybe thats just it for some of us, forget the levels its more due to with how our bodies use it and respond to them for what ever reason.

I am now going to start experimenting and severely reducing my dose to 70-100mg weekly to see how I feel and if I can escape AIs altogether. If my physique looks great and energy and sex life stay consistent for the most part with no AI, then I know that is the way to go for me rather then playing cat and mouse with AI.

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Thank you for sharing your some of your journey and your logic moving forward. Solid plan in my opinion and I’ve had the same experiences at similar T dosages.

If I may, what’s your peak/trough TT level at 140 mg/week of what I presume is Test Ester injection? What’s your AI regimen and E2 level?

I wouldn’t call going to 100 mg weekly a severe reduction and great that you are learning how your body responds to different dosages. In my opinion there’s a reason the old standard dosing protocol was 200 mg/week of TC/TE every two weeks. That’s equivalent to 100 mg/week. A reasonable starting TRT dose. Too bad guys are starting out now at 200 mg/week for TRT (it’s sort of like the equivalent of “hey, mines bigger than yours” and “more must be better”.)

200 mg/week and I would be dead or feel like dying after a few months.

Bless you Brother and I wish you the best and look forward to hearing more on your results.

That’s partly why I asked for your peak/trough TT levels on this protocol? You’ve probably just got the enviable Coleman/Levrone genetics :-)! Depending on your TT levels, may be you are on cycle!

Keep up the great work and congrats.

I have tried 100mg E5D, which had me at 818 trough TT and 38 E2 without AI.
When doing EOD, my trough was 1080, no set schedule for AI so the E2 level wasn’t static.
Never measured peak sadly. Forgot that there was one time prior to the AI, EOD E2 was 40.

I am an over responder to AIs, I took 0.5mg of arimidex one time and after total injections equaling 225mg T and a bolus of HCG equaling 500IU, my E2 ended up being only 27 ten days later after the 0.5mg of arimidex. And another time 0.25mg arimidex had me at 20 E2 ten days later on EOD protocol. So in that sense AIs are a slippery slope for me.

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I’ve been having issues myself. For several years I ran 200 mg a week with .5-1mg a week of arimidex and erections were awesome. Somewhere along the line that went to hell. Cialis used to be amazing, I would take it occasionally for fun, but now has limited impact.
My shbg is 10-11. On 40 mg EOD my sensitive estrogen is 80 (<29) and at 24 mg EOD my estrogen is 52 (<29), even though my total T is only 590 ng/dl at both dosages. Going to experiment with 16mg EOD next, which if linear should hopefully lower my estrogen to the 30s.

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Can daily cialis improve erections where it will be better after discontinuing the booster?

Have you got any data or info about cialis and E2? I actually want to try daily cialis, but if it does act against E2 I have to be mindful of how much to lower my test dose.

Daily cialis can restore penile function. I plan to take it the rest of my life.

I currently do this:

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interesting about that nighttime dosing but they only mentioned nocturnal erections as if that’s much significance.

It is significant. That’s when your penis health is maintained with oxygen rich blood. And maintains full size capabilities . Hehe

I could see that train of thought but I wish they checked if it measured over all erection quality and an improvement in sex life. Just seems kind of vague to mention nocturnal erections while you are asleep and not sexually active.

I am thinking of going gung ho to 84mg a week starting next week makes me wonder if I should hold off cialis and see what happens at that dose first, or try 98mg per week instead.