You need to use anastrozole to manage your E2.
SHBG is high because E2 is high and SHBG is not E2 protective. SHBG+E2 is bio-available.
Transdermal T has highest potential for T-->E2 and T-->DHT, and you are high on both.
FT peaks and drops with daily transdermals and FT is then really not a useful lab as the numbers are largely driven by lab timing.
Labs are quite insane, with high T, LH and FSH should be going to zero. Could be something wrong in pituitary and a MRI is needed anyways to rule in/out a prolactin secreting adinoma.
Before prolactin labs: Avoid orgasms or hugging puppies or babies as that increases prolactin.
Not much is going to move prolactin other than Dostinex. Some meds happen increase prolactin and some decrease.
TSH and fT3 down.
Any change in iodine intake?
TSH should be closer to 1.0
Please see last paragraph below.
Please read the stickies found here: https://forums.t-nation.com/t/about-the-t-replacement-category/38/2?u=ksman
- advice for new guys - need more info about you
- things that damage your hormones
- protocol for injections
- finding a TRT doc
Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body's temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.