serum E2=246pg/ml is a balance of T–>E2 aromatization[production] and E2 clearance by the liver. Liver markers AST/ALT may have some expected elevation from training. If FT [not tested] is low, then FT–>E2 is assumed low. Back to liver. Some medications, Rx and OTC can interfere with E2 clearance. With really strange labs, labs should be repeated to confirm.
Serum iron levels are highly changeable and thus should not dictate anything in isolation.
TSH is near 1.0, great.
tT4 is above mid-range
fT3 is well above mid-range
need your history of using iodized salt
need your oral body temperatures - see below
With strong fT3 and if body temperatures are low, suspect elevate rT3 blocking fT3 and adrenal fatigue. However TSH=0.99 does not fit that pattern.
White blood cells may be indication of fighting an infection.
“High iron binding capacity levels typically indicate low levels of iron in the blood.” - see the problem?
RBC - midrange
hemoglobin - midrange
ferritin - low
Any large muscle bruising/injury.
Ferritin shows iron deficiency or iron losses. Mens’ bodies horde iron and when iron is low, we suspect a GI bleed and an occult blood test can rule that in/out, testing for blood in your poop.
Any digestive issues or food sensitives?
Your LH/FSH and thus T will be low because E2 is high.
Lower E2 and things will change.
Should find and fix cause
and should start anastrozole .75mg twice a week ASAP.
Transdermals are a bad idea when training and sweating. If you do TRT, it should be self-injected T with anastrozole to get near E2=22pg/ml and 250iu hCG SC EOD to preserve testes and fertility.
Also test , AM cortisol and DHEA-S [an adrenal hormone].
“Sex-hormone Producing Tumor. Sex-hormone producing adrenal tumors are rare tumors that make too much androgen (i.e. testosterone), estrogen, or both. These tumors are found in 2 out of every million people and can be either benign (adenomas) or malignant (adrenocortical cancer).”
Nolvadex might be useful to block some E2 effects, 10mg/day.
Please read the stickies found here: About the T Replacement Category
- advice for new guys - need more info about you
- things that damage your hormones
- protocol for injections
- finding a TRT doc
Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.
KSman is simply a regular member on this site. Nothing more other than highly active.
I can be a bit abrupt in my replies and recommendations. I have a lot of ground to cover as this forum has become much more active in the last two years. I can’t follow threads that go deep over time. You need to respond to all of my points and requests as soon as possible before you fall off of my radar. The worse problems are guys who ignore issues re thyroid, body temperatures, history of iodized salt. Please do not piss people off saying that lab results are normal, we need lab number and ranges.
The value that you get out of this process and forum depends on your effort and performance. The bulk of your learning is reading/studying the suggested stickies.