Hi Everyone,
I hope you all doing good. I want to share my story here and hope to have some opinion or advice from others with similar problems. I had following symptoms,
•Total Loss of interest in sex. Erectile dysfunction
•Always feel weakness & Get Tired quickly
•Head pressure and pain behind eyes and sometimes throat as well
•Fat around waist & hips. Skinny arms and hard to put muscle no matter what
•Can’t grow beard and body hairs at age of 27
•Lack of motivation & ability to put focus stay all day at room and becoming anti social
•Feeling of getting scared when think about going outside for normal things like going grocery, bank etc. Getting anxiety/depress after thinking of all that
My first visit to doctor was AUGUST 2016 and following tests were done:
Total Testosterone 297 ng/dl (270-1070)
TSH 1.88 mlu/L(0.40-4.40)
SHBG 14.5 nmol/L (13.3-88.5)
Total T3 1.58nmol/L(1.34-2.73)
Free T4 12.5 Pmol/L (12-22)
Estrone 381 pmol/L (74-185)
LH 5.6 IUS/Liter (2.5-16.3)
FSH 5.3 IUS/Liter (1.2-18.5)
Estradiol 108 pmol/L (<=206)
Prolactin 4.1 ug/L (2.6-13.1)
Testosterone Bioavailable 7.28 nmol/l (3.60-11.30)
ALT 61 u/l (10-40)
Thyroglobluin 3.7 ug/l (1.6-50)
Thyogloubin Antibody <0.9 kIu/l (<=4.9)
Calcium Total 2.63 m/l (2.12-2.62)
As per result, my Estrone was high so I was put on Arimidex (1mg) daily by my doctor. At the start I felt really good but after sometime I had all same symptoms like before. After few Months I had my blood test again.
MAY 2017
Total Testosterone 518 ng/dl (270-1070)
Testosterone Bioavailable 11.37 nmol/l (3.60-11.30)
TSH 1.65 mlu/L(0.40-4.40)
Free T4 16 Pmol/L (12-22)
SHBG 22.3 nmol/L (13.3-88.5)
LH 7.2 IUS/Liter (2.5-16.3)
FSH 8.1 IUS/Liter (1.2-18.5)
Estradiol 73 pmol/L (<=206)
TGMH 26pg (28-33)
Globules blancs 12.9 (4.4-10.8)
Lympho 4.5 (1-4.4)
Creatinine Serum 64 umol/l (80-120)
ALT 50 u/l (10-40)
Doctor adviced me to keep taking Arimidex and do regular exercise at gym, which I already was doing but having no results. Anyway I did blood test after 3 months:
September 2017
Total Testosterone 592 ng/dl (270-1070)
Testosterone Bioavailable 14.82 nmol/l (3.60-11.30)
TSH 1.68mlu/L (0.40-4.40)
SHBG 16.3 nmol/L (13.3-88.5)
Estrone 207 pmol/L (74-185)
LH 12.1 IUS/Liter (2.5-16.3)
FSH 8.7 IUS/Liter (1.2-18.5)
Estradiol <73 pmol/L (<=206)
Prolactin 4 ug/L (2.6-13.1)
ALT 30 u/l (10-40)
I didn’t felt much difference so I planned to change my doctor. Meanwhile I stopped arimidex and New doctor send me for some extra blood tests to have better picture.
March 2018
Total Testosterone 672 ng/dl (270-1070)
Testosterone Bioavailable 14.5 nmol/l (5-18.8)
TSH 2.96 mlu/L (0.40-4.40)
SHBG 23 nmol/L (13-50)
LH 11 U/L (2-9)
Estradiol 53 pmol/L (<=206)
TGMH 26.5 pg (28-33)
Anti-TPO 42 KU/L (0-60)
Thyroglobluin 3.9 ug/l (1.6-50)
Thyogloubin Antibody <0.9 kIu/l (<=4.9)
He also did thyroid ultrasound. He said my thyroid was quite small so it could be hypothyroidism and put me on Synthyroid and letrozole (replacement of Arimidex). Blood Test when were taking synthyroid plus letrozole was.
August 2018
Total Testosterone 855 ng/dl (270-1070)
Free T3 7.3 Pmol/L (4-5.7)
LH 15.44 U/L (1.7-8.6)
FSH 17.07 IUS/Liter (1.2-18.5)
Estradiol 100 pmol/L (<=206)
Cortisol 255 nmol/L (166-828)
ACTH 6.8 PMOL/l(2-11)
My synthyroid dose was increased and during that time I really start feeling worst. Finally I did the blood test and everything was messed up:
March 2019
Total Testosterone 1015 ng/dl (270-1070)
TSH 0.12 mlu/L (0.27-4.2)
Free T3 5.7 Pmol/L (3.1-6.8)
Free T4 23.3 Pmol/L (12-22)
Estradiol 77 pmol/L (94.8-223)
Testosterone Bioavailable 23.480 nmol/l (4.36-14.3)
Meanwhile i was also diagnosed with H.pylori and got treatment for it. I stopped Synthyroid and was put on Ritalin. I also had MRI to rule out pituitary tumor. It was all perfect up there according to neurologist. Now I am just taking arimidex 1mg twice a week.
May 2019
Total Testosterone 660 ng/dl (270-1070)
TSH 2.44 mlu/L (0.27-4.2)
Free T3 5.7 Pmol/L (3.1-6.8)
Free T4 19.9 Pmol/L (12-22)
LH 11 U/L (1.7-8.6)
FSH 7.5 IUS/Liter (1.5-12.4)
Estradiol 43 pmol/L (94.8-223)
Cortisol 397nmol/L (68.2-537)
ACTH 6.8 PMOL/l(2-11)
Testosterone Bioavailable 14.046 nmol/l (4.36-14.3)
Prolactin 14.5 ug/L (4.04-15.2)
Insulin Growth Factor 164ug/L (63-373)
After 3 years of journey and spending so much money I rarely felt any change in my symptoms. Now it’s worse than before. all symptoms. Now I am more depress because all of this and almost giving up. I will really appreciate if anyone can give any useful advice or suggestion,
Thanks